ALL THE COMSAE
Giardia lamblia - ANS tinidazole or nitazoxanide (alt: metronidazole)
Entamoeba histolytica - ANS metronidazole or tinidazole, then paromomycin or iodoquinol
Ascaris lumbricoides - ANS albendazole or mebendazole
Necator americanus - ANS albendazole (alt: mebendazole)
Trichinella spiralis - ANS albendazole + prednisone
Enterobius vermicularis - ANS mebendazole
Schistosoma spp. - ANS praziquantel
Diphyllobothrium latum - ANS praziquantel (alt: niclosamide)
Yersinia Pestis - ANS Streptomycin (alt: gentamicin
Adenovirus (severe infection) - ANS cidofovir + probenecid
Influenza A (seasonal), Influenza B, adn avian flu (H5N1) - ANS zanamivir or oseltamivir
Measles - ANS -Children: vitamin A
-Adults: ribavirin
Smallpox - ANS smallpox vaccine within 4 days of exposure + cidofovir + probenecid
Osteomyelitis (<4 months old) - ANS nafcillin or oxacillin + ceftazidime or cefepime
Osteomyelitis (4 months - adult) - ANS nafcillin or oxacillin
Herpes Encephalitis - ANS -acyclovir
-if HSV (+): acyclovir
-If not HSV (+): DOC for specific etiologic agent
Encephalitis due to Rickettsia, Anaplasma, Ehrlichia, Bartonella, or Mycoplasma - ANS
Doxycycline
Encephalitis due to Borrelia burgdorferi - ANS Ceftriaxone
, Meningitis in neonate, child, or adult - ANS ampicillin + cefotaxime + gentamicin + ceftriaxone
or cefotaxime + dexamethasone + vancomycin
Meningitis in alcoholics, people >50, people with severe comorbid diseases, or anyone who is
immunocompromised - ANS ceftriaxone or cefotaxime + dexamethasone + vancomycin +
ampicillin
Meningitis prophylaxis if haemophilus influenzae - ANS rifampin
Meningitis prophylaxis if neisseria meningitidis - ANS rifampin or ceftriaxone or ciprofloxacin
Otitis externa - ANS acetic acid + propylene glycol + hydrocortisone drops
or
Cirpofloxacin + hydrocortisone drops
Otitis media - ANS -amoxicillin if <2 y/o
-analgesics if >2 with no pain or fever
Viral conjunctivitis - ANS nothing or chilled artificial tears
Bacterial conjunctivitis - ANS fluoroquinolone drops
Neonatal conjunctivitis with onset within 1st day of life - ANS nothing
Neonatal conjunctivitis with onset within 2-4 days of life - ANS IV ceftriaxone + PO erythromycin
Neonatal conjunctivitis with onset within 3-10 days of life - ANS PO erythromycin
Neonatal conjunctivitis with onset within 2-16 days of life - ANS topical antivirals + IV acyclovir
Ophthalmia neonatorum prophylaxis - ANS tetracycline ointment or erythromycin ointment
Post-antibiotic diarrhea - ANS Metronidazole
Travel associated diarrhea - ANS fluoroquinolone or rifaximin
-if a child or pregnant: azithromycin
Diarrhea prophylaxis during travel - ANS fluoroquinolone + loperamide with first loose stool
Mild-moderate diarrhea - ANS fluids + lactose and caffeine free diet
-may add antidiarrheal agents if >4 loose stools/day
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