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Exam- AIDS - N5315 Advanced Pathophysiology Questions & Answers
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Exam- AIDS - N5315 Advanced PathophysiologyQuestions & Answers
HIV 1 and HIV 2 Correct-What are the two types of HIV?
HIV 1 Correct-Which type of HIV is the most common?
Western Africa Correct-Where is HIV 2 mainly seen?
There is one gene that is different between the two viruses. This difference makes HIV 2 much
less virulent and is not as easily transmitted. Correct-What is the difference between HIV 1
and HIV2?
Viral envelope Correct-What is HIV covered with?
gp 120 Correct-What is the protein protruding from HIV?
An HIV specific protein Correct-What is gp 120?
, Exam- AIDS - N5315 Advanced Pathophysiology
Questions & Answers
Enzymes which it uses for replication (reverse transcriptase, integrase and protease)
Correct-What does the HIV virus carry inside it?
The capsid Correct-What are HIV virus enzymes encased in?
CD4 cell Correct-What is the target cell for HIV?
CD4 receptor, CCR5 receptor and the CXCR4 receptor. Correct-What are the 3 receptors on
the CD4 cell membrane that are important to HIV?
HIV gp 120 binds to CD4 receptor and one of the other 2 receptors (CCR5 or CXCR4); gp 120
fuses with CD4 cell; viral RNA injected into cell cytoplasm; viral RNA then uncoated (capsid
removed) and enzyme reverse transcripase used to make DNA from the viral RNA; viral DNA
then travels to nucleus of cell where it is integrated into the host cell's DNA using enzyme
integrase; transcription begins which causes DNA to make new viral RNA particles; at
completion of transcription, translation begins and new viral proteins are produced; viral
proteins then gather beneath the cell membrane and a capsid is formed around them; it then
buds through the cell membrane and obtains a viral envelope; viral maturation occurs after
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