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Exam- N5315 Advanced Pathophysiology Quiz 2| Immune System and Infectious Disease
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Exam- N5315 Advanced Pathophysiology Quiz 2|Immune System and Infectious Disease
What are the 5 types of Immunity? Correct--Natural Immunity (Innate
Resistance/Immunity)
-Acquired Immunity
-Passive Acquired Immunity
-Humoral Immunity
-Cell-Mediated Immunity
Define Natural Immunity (Innate Resistance/Immunity): Correct--resistance that exist prior
to exposure to a microbe
-we are born with this resistance
-based on genotypes and species
What nonspecific barriers to infection does Natural Immunity provide? Correct--skin
-mucous membranes
-certain cells (NK cells)
-certain proteins (complement cytokines)
-inflammation
, Exam- N5315 Advanced Pathophysiology Quiz 2|
Immune System and Infectious Disease
-phagocytosis
-does not improve at exposure
-functions to kill invading microorganisms and activates acquired immunity
Name the cells of innate immunity? Correct--phagocytic cells
-antigen presenting cells
-natural killer cells
-complement
Define Phagocytic cells: Correct--cell of innate immunity (Natural Immunity or Innate
Resistance/Immunity)
-includes: Neutrophils, Macrophages, Dendritic Cells
Define Neutrophils: Correct--present during acute inflammation
-responsible for engulfing microbes & kills them by using cytoplasmic myeloperoxidase
, Exam- N5315 Advanced Pathophysiology Quiz 2|
Immune System and Infectious Disease
Cytoplasmic Myeloperoxidase is toxic to ? Correct-Pathogens
Define Macrophages: Correct--derived from monocytes, which leave the blood stream and
differentiate tissues
Define Dendritic Cells: Correct--engulf antigens in the epithelia of skin, GI and respiratory
trace
Define Antigen presenting cells (APC): Correct--dendritic cells, macrophages and B cells
-Ingest and process antigens
-peptides loaded on to their major histocompatibility complex II molecule & presented to T
Cell
Define Natural Killer Cells: Correct--contain granules that attack & kill virus-infected or
cancer cells
, Exam- N5315 Advanced Pathophysiology Quiz 2|
Immune System and Infectious Disease
Define Complement: Correct--compromised of collection of proteins formed by cascade of
events
-they form the membrane attack complex and lyse a pathogen's cell membrance
Define acquired immunity: Correct-Acquired or adaptive immunity develops in response to
exposure to a foreign or nonself substance. The cells involved are memory cells that provide
long-term protection against specific antigens. Acquired immunity is obtained from the
development of antibodies when the human is exposed to an antigen or is obtained as the
result of a vaccination or an attack of an infectious disease. Acquired immunity can be the
result of the transmission of antibodies from mother to fetus via the placenta.
What immunity is the basis of Vaccinations? Correct-Acquired Immunity
Define Passive Immunity: Correct-- immunity that results from the introduction of
antibodies or T-cells from another person or animal.
What are the 2 passive acquired immunities? Correct--Natural Passive Immunity
-Artificial Passive Immunity
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