2024/25 Mock ACLAM Practice
Written/Practical Examination Newest
Rated A+
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Answer: c. Alouattinae and Atelinae
References:
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1) Abee CR, Mansfield K, Tardif S, Morris T, eds. 2012. Nonhuman Primates in Biomedical
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Research, 2nd edition, Volume 1 - Biology and Management, Academic Press: San Diego,
CA. Chapter 4 – Functional Morphology, pp. 105-106.
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2) Fox JG, Anderson LC, Otto G, Pritchett-Corning KR, Whary MT, eds. 2015. Laboratory
Animal Medicine, 3rd edition. Academic Press: San Diego, CA. Chapter 17 – Nonhuman
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Primates, pp. 775, 777. ll ll ll ll ll ll ll
Domain 1; Tertiary Species - Other Nonhuman Primates
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Which two subfamilies of new world monkeys possess a prehensile tail with a tactile pad?
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a. Cebinae and Pithecinae
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b. Aotinae and Callicebinae
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c. Alouattinae and Atelinae
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d. Cercopithecine and Colobinae ll ll ll ll ll ll ll ll ll ll ll
Answer: a. Algorithms used to compare BIS are based on human data
References:
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1) Fox JG, Anderson LC, Otto G, Pritchett-Corning KR, Whary MT, eds. 2015. Laboratory
Animal Medicine, 3rd edition. Academic Press: San Diego, CA. Chapter 24 –
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Preanesthesia, Anesthesia, Analgesia, and Euthanasia, pp. 1184-1185.
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2) Jaber et al. 2015. Comparison of heart rate and blood pressure with toe pinch and
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bispectral index for monitoring the depth of anesthesia in piglets. JAALAS 54(5):536-544.
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Which of the following is a drawback to the use of bispectral index (BIS) for anesthetic
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depth monitoring of laboratory animals?
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a. Algorithms used to compare BIS are based on human data
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b. It is an invasive procedure
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c. There is no data to support its use in common laboratory animals
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d.It can only be used for injectable anesthetic regimens ll ll
Answer: b. Wistar
References:
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1) Fox JG, Anderson LC, Otto G, Pritchett-Corning KR, Whary MT, eds. 2015. Laboratory
Animal Medicine, 3rd edition. Academic Press: San Diego, CA. Chapter 4 – Biology and
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Diseases of Rats, pp. 152, 193-194.
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2) Suckow MA, Weisbroth SH, Franklin CL, eds. 2006. The Laboratory Rat, 2nd edition.
Elsevier Academic Press: San Diego, CA. Chapter 15 – Metabolic, Traumatic, and
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Miscellaneous Diseases, pp. 534-535.
,Domain 3; Primary Species – Rat (Rattus norvegicus)
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What stock of rats has been reported to have a high incidence of seizures and has been
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used in investigation of audiogenic seizures?
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a. Albany
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b. Wistar
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c. Sprague-Dawley
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d. Holtzman
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Answer: c. Environmental enrichment strategies should elicit species specific
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behavior
References:
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1) Collymore et al. 2015. The behavioral effects of single housing and environmental
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enrichment on adult zebrafish (Danio rerio). JAALAS 54(3):280-285.
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2) Institute for Laboratory Animal Resources. 2011. Guide for the Care and Use of
Laboratory Animals. National Academy Press, Washington, D.C. Chapter 3 –
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Environment, Housing, and Management, pp. 82-83.
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3) Fox JG, Anderson LC, Otto G, Pritchett-Corning KR, Whary MT, eds. 2015. Laboratory
Animal Medicine, 3rd edition. Academic Press: San Diego, CA. Chapter 20 – The Biology
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and Management of the Zebrafish, p. 1023.
Domain 4; Secondary Species – Zebrafish (Danio rerio)
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Which of the following statements best describes environmental enrichment strategies for
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adult zebrafish?
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a. Environmental enrichment strategies in zebrafish should not include artificial material
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b. Environmental enrichment strategies for zebrafish are well established in the literature
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c. Environmental enrichment strategies should elicit species specific behavior
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d. Environmental enrichment strategies should only be used for group housed zebrafish
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e. Environmental enrichment strategies should only be used for juvenile zebrafish
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Answer: a. 4
Reference: Animal Welfare Regulations, CFR Title 9, Chapter 1, Subchapter A – Animal
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Welfare, Part 3 – Standards, Subpart A – Specifications for the Humane Handling, Care,
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Treatment, and Transportation of Dogs and Cats, §3.6 (b)(2) Primary enclosures (11-6-13
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Edition, p. 65)
(http://www.aphis.usda.gov/animal_welfare/downloads/Animal%20Care%20Blue%20Bo
ok%20-%202013%20-%20FINAL.pdf)
Domain 5; Primary Species – Dog (Canis familiaris)
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Puppies under _____ months of age may not be housed in the same primary enclosure
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with adult dogs, other than the dam or foster dam, except when permanently maintained in
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breeding colonies?
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a. 4
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b. 5 ll
c. 6 ll
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Answer: a. Beagle Freedom Project ll
Reference: http://www.identitycampaign.org/
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Which of the following organizations has recently used "The Identify Campaign" as a fund
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raiser which "adopts" animals to donors and provides information to the donor on how to
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obtain additional information on their "adopted" pet from the institution through an open
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records request?
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a. Beagle Freedom Project
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b. Beagle Rescue League
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c. Humane Society of the United States
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d. National Biomedical Research Association
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e. People for the Ethical Treatment of Animals ll ll ll
Answer: d. Listeria monocytogenes
References:
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1) Suckow MA, Stevens KA, Wilson RP, eds. 2012. The Laboratory Rabbit, Guinea Pig,
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Hamster, and Other Rodents. Academic Press: San Diego, CA. Section III - Guinea Pigs,
Chapter 23 – Infectious Diseases, pp. 652-653 656-657,
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2) Percy DH and Barthold SW. 2007. Pathology of Laboratory Rodents and Rabbits, 3rd
ed. Blackwell Publishing: Ames, Iowa. Chapter 5 – Guinea Pig, p. 228.
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Domain 1; Secondary Species – Guinea Pig (Cavia porcellus)
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Guinea pigs are highly susceptible to an infection associated with high mortality, acute
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death, reproductive disorders, as well as lung and liver lesions with which of the following
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bacterial organisms?
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a. Brachyspira hyodysenteriae
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b. Chlamydophilia caviae
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c. Leptospira spp.
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d. Listeria monocytogenes ll ll
Answer: b. 5°C
References:
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1) Fox JG LC, Anderson, Otto G, Pritchett-Corning KR, Whary MT, eds. 2015. Laboratory
Animal Medicine, 3rd edition. Academic Press: San Diego, CA. Chapter 5 – Biology and
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Disease of Hamsters, p. 215.
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2) Suckow MA, Stevens KA, Wilson RP, eds. 2012. The Laboratory Rabbit, Guinea Pig,
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Hamster, and Other Rodents. Academic Press: San Diego, CA. Section IV - Hamsters,
Chapter 36 – European Hamster, p. 931
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Domain 3; Tertiary Species – Other Rodents
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At what temperature will hibernation occur in Cricetus cricetus?
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a. 3°C
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b. 5°C
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c. 8°C
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d. 10°C ll ll ll ll ll ll ll ll ll
Answer: b Static microisolator, 70% relative humidity, wood pulp bedding
, References:
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1) Institute for Laboratory Animal Resources. 2011. Guide for the Care and Use of
Laboratory Animals. National Academy Press, Washington, D.C. Chapter 3 –
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Environment, Housing, and Management, pp. 45, 71.
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2) Silverman et al. 2008. Ammonia and carbon dioxide concentrations in disposable and
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reusable ventilated mouse cages. JAALAS 47(2):57-62.
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3) Fox JG, Barthold SW, Davisson MT, Newcomer CE, Quimby FW, Smith AL, eds. 2007.
The Mouse in Biomedical Research, 2nd edition, Volume 3 – Normative Biology,
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Husbandry, and Models. Academic Press: San Diego, CA. Chapter 9 – Design and
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Management of Research Facilities for Mice, p. 293.
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4) Ferrecchia et al. 2014. Intracage ammonia levels in static and individually ventilated
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cages housing C57BL/6 mice on 4 bedding substrates. JAALAS 53(2):146-151
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Domain 4; Primary Species - Mouse (Mus musculus)
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All other things being equal, which of the following caging conditions for mice would have
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the highest ammonia level?
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a. Static microisolator, 70% relative humidity, corncob bedding
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b. Static microisolator, 70% relative humidity, wood pulp bedding
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c. Static microisolator, 30% relative humidity, corncob bedding
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d. Individually ventilated microisolator, 70% relative humidity, wood pulp bedding
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e. Individually ventilated microisolator,30% relative humidity, corncob bedding
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Answer: c. 1 business day
References:
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1) Fish RE, Brown MJ, Danneman PJ, Karas AZ, eds. 2008. Anesthesia and Analgesia in
Laboratory Animals, 2nd ed. Academic Press, San Diego, CA. Chapter 25 – Regulatory
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Issues, p. 575.
2) Controlled Substances Act, USC Title 21, Section 831, Subchapter I – Control and
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Enforcement, Part C – Registration of Manufacturers, Distributors, and Dispensers of
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Controlled Substances. §813 Additional requirements relating to online pharmacies and
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telemedicine.
3) Title 21 Code of Federal Regulations, Part 1301 — Registration Of Manufacturers,
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Distributors, And Dispensers Of Controlled Substances; Security Requirements,
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§1301.76 (b) Other security controls for practitioners. ll
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Theft or "significant loss" of controlled substances requires immediate reporting to the DEA
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upon discovery of the loss or theft within how many hours?
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a. 24 hours
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b. 48 hours
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c. 1 business day
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d. 1 week ll ll
Answer: b. Chorioptes