Clayton’s Basic Pharmacology for Nurses 19th Edition TEST BANK By Michelle J. Willihnganz, Samuel L. Gurevitz
Clayton’s Basic Pharmacology for Nurses 19th Edition TEST BANK By Michelle J. Willihnganz, Samuel L. Gurevitz
Complete Test Bank Claytons Basic Pharmacology for Nurses 19th Edition Willihnganz Questions & Answers with rationales (Chapter 1-48) GRADED A
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Clayton’s Basic Pharmacology for Nurses 19th Edition
TEST BANK By Michelle J. Willihnganz, Samuel L.
Gurevitz
Factors that affect drug therapy - ANSWER:age, body weight, gender, metabolic rate,
illness, psychology, tolerance, dependence, cumulative effect
Most sensitive - ANSWER:Infants and very old tend to be______to the effects of
drugs
Patients who are overweight may require - ANSWER:An increase in drug dosage to
attain the same therapeutic response
Patients who are under weight compared with the general population -
ANSWER:Tend to require lower dosages for the same therapeutic response
Most Pediatric dosage are calculated - ANSWER:by milligrams for drug per kilogram
of body weight
Gender specific medicine - ANSWER:A developing science that studies differences in
the normal function of men and women and addresses how people of each gender
perceive and experience disease.
Patient with hired an average metabolic rate - ANSWER:Require larger doses or more
frequent administration
Patients with lower than average metabolic rates - ANSWER:Require lower dosage
and less frequently
Chronic smoking enhances the metabolism of some drugs thereby requiring dose to
be administered - ANSWER:more frequently for therapeutic effect
Pathologic conditions may alter the rate of - ANSWER:Absorption, distribution,
metabolism and excretion of a drug
Patients who are in shock have reduced peripheral vascular circulation and will -
ANSWER:Absorb intramuscular or subcutaneously injected drugs more slowly
Patients who are vomiting may not be able to - ANSWER:Retain a medication long
enough for dissolution and absorption
Patience with nephrotic syndrome or malnutrition may have a reduced amount of -
ANSWER:Serum proteins in the blood that are necessary for adequate distribution of
drugs
, Patience with kidney failure generally will excrete drugs at a - ANSWER:slower rate
and must have significant reductions in dosage of medication excreted by the
kidneys
Placebo effect - ANSWER:Patient's positive expectation about treatment and the
care receive can possibly if affect the outcome of therapy
nocebo effect - ANSWER:a negative placebo effect due to the expectation of adverse
consequences from receiving treatment
Placebo - ANSWER:A drug dosage form that has no pharmacologic activity Because
the dosage form has no active ingredients
Tolerance - ANSWER:Occurs when a person begins to require a higher dosage of a
medication to produce the same affect that a lower dosage ones provided
Drug dependence - ANSWER:Occurs when a person is unable to control a desire for
ingestion of drugs
Drug accumulation - ANSWER:accumulation in the body may occur if the next dose is
admin. before the previously admin. dose has been metabolized or excreted
Carcinogenicity - ANSWER:The ability of a drug to induce living cells to mutate and
become cancerous.
Factors that influence drug actions - ANSWER:absorption, distribution, metabolism,
excretion (ADME)
Factors that influence drug absorption in Age - ANSWER:Pediatric and geriatric
patient require special consideration for medication administration
neonates and older adults - ANSWER:Medicine given intramuscularly are usually
erratically absorbed in
Infants - ANSWER:Topical administration with percutaneous absorption is usually
effective for
Children or any patient with loose teeth - ANSWER:Chewable tablets should not be
giving to
Passive diffusion - ANSWER:Across the membrane by gastric emptying time depend
on the pH of the environment
Newborns and geriatric patients have - ANSWER:Reduce gastric acidity and prolong
transit time compared with adults
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