potency is related to
dose. Potency is greater when a dose is smaller
efficacy is
the maximum response of a drug regardless of dose
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Brainpower
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What is first past effec...
potency is related to - ANSWER- dose. Potency is greater when a dose is smaller
efficacy is - ANSWER- the maximum response of a drug regardless of dose
What is first past effect? - ANSWER- When orally administered drugs pass
through the hepatic portal which reduces the amount effective drug. this requires
large doses of a drug
What drug administration route is used to deliver protein products? - ANSWER-
Subcutaneous
The TB skin test is an example of what route of drug administration? - ANSWER-
Intradermal
The study of how we drug enters the body, circulates in the body and leaves the
body - ANSWER- pharmacokinetics
What organ is involved in absorption of oral drugs? - ANSWER- small intestine
What is the most important site for metabolism of drugs? - ANSWER- the liver
What is the most important organ that is involved in excretion? - ANSWER-
kidneys
What terminates drug effects? - ANSWER- elimination
What steps do intra-vascular drugs bypass? - ANSWER- absorption and first pass
What drugs are known to move across biological membranes by diffusion? -
ANSWER- Lipid soluble drugs
,Metabolism is also known as - ANSWER- Bio transformation
Side effects are - ANSWER- Dose related reaction that is not part of the desired
therapeutic action
True or false: an allergic reaction is related to dose - ANSWER- false
An abnormal drug response that is usually genetically determined - ANSWER-
Idiosyncrasy
What are the two branches of the autonomic nervous system? - ANSWER-
Sympathetic and parasympathetic
What are some effects of the sympathetic nervous system? - ANSWER- Fight or
flight
Increase blood pressure through vasoconstriction
Dilate pupils and bronchioles
Reduce salivary flow
The preganglionic neurotransmitter for the sympathetic nervous system is -
ANSWER- Acetylcholine
The Post ganglionic neurotransmitter for the sympathetic nervous system is -
ANSWER- Norepinephrine
What drugs mimic the sympathetic nervous system? - ANSWER- Adrenergic
drugs
What diseases should avoid adrenergic drugs? - ANSWER- angina, uncontrolled
hypertension and uncontrolled hyperthyroidism
What is dopamine used to treat? And what class of drugs is it? - ANSWER-
Shock, Low blood pressure, parkinson's. adrenergic
Andrenergic blocking drugs are used to treat - ANSWER- High blood pressure,
angina, glaucoma and myocardial infarction
Propanolol is also known as:
And it is a - ANSWER- Inderal
Nonselective beta blocker to treat hypertension
, Atenolol is also known as:
And it is a - ANSWER- Tenormin
Selective beta blocker to treat hypertension
Lopressor is also known as
And it is a - ANSWER- Metoprolol
selective beta blocker to treat hypertension
pilocarpine is an example of a:
what two diseases can it treat? - ANSWER- cholinergic drug.
It increases saliva flow in patients with sjogrens
can also tx glaucoma
what type of drugs are used to treat hypertension and angina? - ANSWER-
adrenergic blocking
what drugs are contraindicated for angina, uncontrolled hypertension and
hyperthyroidism? - ANSWER- adrenergic drugs
mechanism of action for aspirin - ANSWER- inhibits prostaglandin synthesis
the A's of Aspirin - ANSWER- Analgesic
antipyretic
Anti inflammatory
anti platelet
what is synergism - ANSWER- when the combo of two antibiotics produces a
greater effect than if just one were used
contraindications for aspirin - ANSWER- asthma, coumadin, stomach ulcers and
children (especially with the flu and chicken pox)
What Gi side effect is related to aspirin? - ANSWER- ulcers
what % of patients have an allergy to aspirin? what patients are more at risk? -
ANSWER- 15%, asthma patients
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