Exam (elaborations)
MLS set - CSMLS EXAM QUESTIONS
- Course
- Institution
MLS set - CSMLS MLS set - CSMLS MLS set - CSMLS
[Show more]
Seller
Follow
Content preview
MLS set - CSMLSWhich bleeding disorder is an inherited lack of fibrinogen, often diagnosed by umbilical bleeding?
(TT, PT, and APTT all increased) - verified answer Afibrinogenemia
What is the factor name of HMWK? - verified answer Fitzgerald factor
What is the factor name of prekallikrein? - verified answer Fletcher factor
What is the name of factor XIII? - verified answer Fibrin stabilizing factor
What is the name of factor XII? - verified answer Hageman factor
What is the name of factor XI? - verified answer Plasma thromboplastin antecedent
What is the name of factor X? - verified answer Stuart-Prower factor
What is the name of factor IX? - verified answer Christmas factor
What is the name of factor VIII? - verified answer Anti-hemophilic factor
What is the name of factor VII? - verified answer Stable factor
Which factor deteriorates at RT? - verified answer Factor V
What is the name of factor V? - verified answer Labile factor
What is the name of factor IV? - verified answer Ca2+
What is the name of factor III? - verified answer Tissue thromboplastin
,What is the name of factor II? - verified answer Prothrombin
What is the name of factor I? - verified answer Fibrinogen
Which factors are consumed during clotting? - verified answer I, V, VIII, XIII
What are acquired pathologic plasma proteins - usually IgG Abs against factors - that inhibit
coagulation? - verified answer Circulating anticoagulants
A test in which abnormal patient plasma is mixed 1:1 with normal control plasma and the mixture is
used for PT/APTT tests. If the abnormal result is not corrected, a circulating anticoagulant is
detected. - verified answer 1:1 mix test
What is the critical value for INR? - verified answer >5.0
When should a patient have an APTT result that is 1.5-2x the normal value? - verified answer
Heparin therapy
Which coagulation test measures the factors of the intrinsic and common pathways and is used to
monitor patients on heparin therapy? - verified answer APTT
When should a patient have a PT result that is 1.5-2x the normal value? - verified answer Coudamin
(warfarin) therapy
Which coagulation test detects deficiencies in the extrinsic and common pathway factors and is used
to calculate INR to monitor patients on warfarin therapy? - verified answer PT
Which coagulation test measures the time required for thrombin to convert fibrinogen to fibrin? -
verified answer TT
Which coagulation test measures platelet number and function? - verified answer Bleeding time
,What is caused by arterial thrombosis in the brain? - verified answer Stroke
What is caused by arterial thrombosis in the heart? - verified answer AMI
What is caused by arterial thrombosis in the limb? - verified answer Gangrene
How does plasmin activate complement? - verified answer Cleaves C3 into C3a and C3b
What is the name of C3a? - verified answer Anaphylatoxin
What is the name of C3b? - verified answer Opsonin
What does warfarin inhibit? - verified answer Vitamin K
What is a vitamin K dependent protease inhibitor that acts as a co-factor for Protein C? - verified
answer Protein S
What is a vitamin K dependent protease inhibitor that is activated by thrombin and degrades factors
V and VIII:C? - verified answer Protein C
Which protease inhibitor is the major natural inhibitor, also called heparin co-factor because it is
greatly accelerated by heparin, and is the major inactivator of thrombin and Xa? - verified answer
Antithrombin III (ATIII)
What is the main inhibitor of plasmin and inhibits rapidly? - verified answer Alpha 2 antiplasmin
What is a plasmin inhibitor that inhibits slowly? - verified answer Alpha 2 macroglobulin
What enzyme is responsible for hydrolyzing fibrin, fibrinogen and other coagulation proteins? -
verified answer Plasmin
, What system is activated when plasminogen that is bound to fibrin is converted to plasmin by TPA? -
verified answer Fibrinolytic system
What system results in enzymatic cleavage of the fibrin clot to soluble fragments to re-establish
blood flow? - verified answer Fibrinolytic system
What factors are involved in the common pathway? - verified answer I, II, V, X
Which coagulation tests can monitor the common pathway? - verified answer PT and APTT
Which pathway begins with the activation of factor X by the intrinsic and/or extrinsic pathway? -
verified answer Common
Which portion of factor VIII is the smallest portion, called the procoagulant protein or anti-
hemophilic portion, and acts as a co-factor for factor IXa to activate factor X in the intrinsic pathway?
- verified answer VIII:C
Which portion of factor VIII is the larger portion, called the carrier portion, and is necessary for
platelet adhesion to tissue? - verified answer VWF
Activation of which factor activates the intrinsic pathway, inflammation (prekallikrein), fibrinolysis,
and complement? - verified answer XII
Which factors are needed to amplify the contact factors to speed up the intrinsic pathway? -
verified answer Fletcher and Fitzgerald
Which factors are involved in the intrinsic pathway? - verified answer XII, XI, IX, VIII, Fletcher,
Fitzgerald
Which factors are involved in the extrinsic pathway? - verified answer III, VII
High molecular weight proteins that are consumed during clotting and are acted on by thrombin to
convert fibrinogen to fibrin, includes factors I, V, VIII, and XIII - verified answer Fibrinogen proteins
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller Josephk. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $15.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
78834 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now