What is Chlorpromazine? Right Ans - A typical antipsychotic
Treats chronic hiccups & its used as an antiemetic
Chlorpromazine Adverse Effects for FGAs Right Ans - •Sedation
•Orthostatic hypotension
•Anticholinergic effects
•Cardiac dysrhythmias
•NMS
•EPS : Tardive dyskinesia; Can be IRREVERSIBLE
What do Typical Antipsychotics (FGAs) do? Right Ans - Block a variety of
receptors within/out CNS:
-Dopamine (EPS- Parkinsonism)
-Acetylcholine (Anticholinergic effects)
-Histamine (Drowsiness)
- Norepinephrine (BP and HR drop)
When taken chronically, can greatly reduce relapse of schizo.
Initial effects may be seen in 1-2 days.
Are all FGAs the same? Right Ans - They are all equally effective, although
individual patients may respond better to one FGA than another
Typical Antipsychotics (FGAs) Red Flag Right Ans - Do not take with other
CNS depressants or alcohol
EPS Tx : Early Stage Right Ans - - Anticholinergics
- Benzodiazepine
- Beta blockers
- Reduce dosage or switch to SGA
EPS Tx: Late Stage Right Ans - - No reliable treatment
- Reduce dosage or switch to SGA
EPS Right Ans - Pseudoparkinsonism
Acute dystonia
, Akathisia
Tardive dyskinesia
What does fluoxetine do? Right Ans - Selective Serotonin Reuptake
Inhibitors (SSRI)
-1- 4weeks for max effectiveness
-Antidepressant generally safe in breast-feeding woman
Patient Education for fluoxetine Right Ans - -Monitor for suicidal ideation
-teach pt to limit grapefruit juice
-can cause serotonin syndrome 2-72 hrs after onset
-Do not stop abruptly
Fluoxetine Side Effects Right Ans - -sexual dysfunction
-insomnia
-nausea
-weight gain
-CNS stimulation
Serotonin Syndrome Right Ans - Occurs when you take meds that cause
high levels of the chemical serotonin which accumulate in your body 2-72 hrs
after treatment onset
St John's Wort a herbal product used for depression, increases rick of
serotonin syndrome
Common Antidepressants for Bipolar Depressive Phase Right Ans -
Atypical: Bupropion
SSRIs: Fluoxetine & Sertraline
SNRIs: Venlafaxine
OCD Medications Right Ans - SSRIs:
-Fluoxetine
-Sertraline
-Paroxetine
Takes serveral months to become max
All 6 SSRIs are equaly effective
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