NUR228 – HYPERSENSITIVITY Exam Questions With Correct And Revised Answers
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Course
NUR 228
Institution
NUR 228
NUR228 – HYPERSENSITIVITY Exam
Questions With Correct And Revised
Answers
What is hypersensitivity? - answerNormal immune response that is
Inappropriately triggered
OR
Excessive (overproducing)
OR
Produces undesirable effects on the body
What are the basic triggers of hypersensitivity? -...
NUR228 – HYPERSENSITIVITY Exam
Questions With Correct And Revised
Answers
What is hypersensitivity? - answer✔✔Normal immune response that is
Inappropriately triggered
OR
Excessive (overproducing)
OR
Produces undesirable effects on the body
What are the basic triggers of hypersensitivity? - answer✔✔Antigen-antibody reaction or
antigen-lymphocyte interaction.
What are the four types of hypersensitivity? - answer✔✔Types I, II, III (mediated by antibodies
produce by B cells that when activated become plasma cells)
Type IV (mediated by T cells)
Which types of hypersensitivity are mediated by antibodies? - answer✔✔Types I, II, III.
Which types of hypersensitivity are mediated by T cells? - answer✔✔Type IV.
What is Type I Hypersensitivity? - answer✔✔Immediate reaction after sensitization to an
antigen.
What are some examples of antigens? - answer✔✔Environmental (pet dander, bee stings), Foods
(nuts, seafood, eggs), Medications (penicillin, contrast dye).
What is the etiology of Type I Hypersensitivity? - answer✔✔Genetic link, with a higher chance
if one or both parents are allergic.
What cells are involved in Type I Hypersensitivity? - answer✔✔B lymphocytes produce
antibodies (IgE), which attach to mast cells.
What is the role of mast cells in Type I Hypersensitivity? - answer✔✔Mast cells circulate around
the body and are part of the immune system.
What are the clinical manifestations of potent vasodilation? - answer✔✔Stuffy nose, Lower
blood pressure, Wheals on skin
What are the clinical manifestations of increased vascular permeability? - answer✔✔Edema,
Runny nose
What are the clinical manifestations of bronchial smooth muscle constriction? -
answer✔✔Breathing difficulties, Wheezing
What is the clinical manifestation of stimulating irritant receptors? - answer✔✔Itching (pruritis)
What are atopic reactions? - answer✔✔Inherited tendency to become sensitive to allergens.
What are some examples of atopic reactions? - answer✔✔Allergic rhinitis, asthma, urticaria.
What are the most common triggers of atopic reactions? - answer✔✔Pollen, dusts, molds, animal
dander.
What is Type I: Anaphylaxis? - answer✔✔Systemic release of chemical mediators throughout
the whole body.
Why is Type I: Anaphylaxis life-threatening? - answer✔✔Bronchial constriction, airway
obstruction, and vascular collapse (shock).
What are the most common triggers of anaphylaxis? - answer✔✔Medications (Penicillin), bee
stings, and foods (Iodine in seafood and peanuts).
The edema and vasodilation resulting from a type 1 hypersensitivity response are caused by: -
answer✔✔Release of chemical mediators
What is Type II Hypersensitivity? - answer✔✔Immune response to antigens on cell surface
What is the etiology of Type II Hypersensitivity? - answer✔✔Exposure to antigen or foreign
tissue/cells
What are the key characteristics of Type II Hypersensitivity? - answer✔✔Antibody production,
cell destruction, lysis, phagocytosis
Which immune cells are involved in Type II Hypersensitivity? - answer✔✔Antibodies (IgG &
IgM), complement, WBCs (phagocytes)
What are examples of antigens in Type II Hypersensitivity? - answer✔✔Blood, body's own cells
(auto-immune conditions), erythroblastosis fetalis
What is a blood transfusion reaction? - answer✔✔An adverse reaction to a blood transfusion.
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