Most common causes of CKD (2)
Diabetes and hypertension
Nephrons primary function
control h2o and sodium
SGLT2 inhibitors work in what part of the nephron?
Proximal tubule
Blood pH is regulated by the exchange of ____ and ____ in the _____ of the nephron
hydrogen and bicarb...
Which two medications are dosed based on eGFR and not CrCl -
answer SGLT2 inhibitors and metformin
MDRD (_____) & CKD-EPI (_____) are used to calculate _____ - answer
MDRD (Modification of Diet in Renal Disease)
CKD-EPI (CKD-Epidemiology Collaboration)
used to calculate eGFR
KDIGO recommends using ____ and ____ to stage CKD - answer
albuminuria and eGFR
On the exam _____ and/or _____ indicate the patient has CKD - answer
GFR <60
albuminuria (ACR* or AER** ≥30)
*Albumin:creatinine ratio
**Albumin excretion rate
When starting treatment with an ACE or ARB, what can happen to
Scr? - answer Scr can increase by up to 30% initially
Monitoring after starting ACE/ARB:
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