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NBME CBSE 2024 EXAM QUSTIONS WITH VERIFIED CORRECT SOLUTIONS $12.49   Add to cart

Exam (elaborations)

NBME CBSE 2024 EXAM QUSTIONS WITH VERIFIED CORRECT SOLUTIONS

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  • NBME CBSE

NBME CBSE 2024 EXAM QUSTIONS WITH VERIFIED CORRECT SOLUTIONS what drug blunts the diuretic effect of *Loops* - ANSWER NSAID (inhibit prostaglandin) ACEi and ARB beneficial in - ANSWER systolic heart failure spironolactone - ANSWER K sparing for ventricular remodeling in CHF and decre...

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  • September 6, 2024
  • 179
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NBME CBSE
  • NBME CBSE
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ProfBenjamin
NBME CBSE 2024 EXAM QUSTIONS
WITH VERIFIED CORRECT
SOLUTIONS

what drug blunts the diuretic effect of *Loops* - ANSWER ✔ NSAID (inhibit
prostaglandin)

ACEi and ARB beneficial in - ANSWER ✔ systolic heart failure

spironolactone - ANSWER ✔ K sparing
for ventricular remodeling in CHF and decreased EF

limiting dose of ACEi - ANSWER ✔ hypotension

Succinylcholine - ANSWER ✔ DEPOLARIZING NM block

biphasic: constant/lesser --> Fade

Vecuronium - ANSWER ✔ NON-DEPOLARZING
NM block
= fade

a1 - ANSWER ✔ bladder (hold)
Mydriasis (dilate)

B1 - ANSWER ✔ Heart (increases contraction and rate)
activates *cAMP*

B2 - ANSWER ✔ vasodilate peripheral bv
bronchodilate
uterus (relax)

, HTN emergency treatment - ANSWER ✔ *Fenoldopam*: peripheral d1-R
agonist

= arteriolar dilation
renal perfusion/natriuresis

AE Nitroprusside - ANSWER ✔ Cyanide poisoning
- red skin

Antidote toxicity of nitrates - ANSWER ✔ inhaling *amyl nitrite*
- generates methemoglobin

*Sodium thiosulfate*
- donates sulfur group --> hydroxycobalamin

Sodium thiosulfate - ANSWER ✔ antidote for CN poisoning

*donates sulfur* group
--> hydroxycobalamin

Why should you not take ACEi with Spironolactone - ANSWER ✔ hyper K
risk

hyperK risk when taking ACEi with - ANSWER ✔ *ARB*
K sparing (SEAT):
- *Aldo Antag: *Spironolactone, Eplernone
- *ENaC Inhib: *Amiloride, Triamterene

Digoxin - ANSWER ✔ *inhibit NaK ATPase*
= decrease Na efflux
= Increase PNS tone

AE Digoxin - ANSWER ✔ hyper K
COLOR vision changes

renally excreted

Adenosine - ANSWER ✔ Block AV node conduction

,= PSVT tx

Adenosine AE - ANSWER ✔ flushing
chest burning
hypotension

coronary steal - ANSWER ✔ ischemic blood flow reduced due to arteriolar
vasodilation of non-ischemic areas

Nitrate (isorbide nitrate) - ANSWER ✔ increase cGMP
decrease Ca
*myosin dephosphorylation*
= RELAX

What must you keep in mind when administering nitrates - ANSWER ✔
NITRATE FREE INTERVAL
- avoid tolerance

do not give Nitrate to individual with - ANSWER ✔ HCM

QT prolongation drugs - ANSWER ✔ *Class IA*: quinidine, procainamide,
disopyramide
*Class III:* amiodarone, ibutilide, *sotalol*, dofetilide
*Macrolides*
*Fluoroquinolone*
*Methadone*
*Haloperidol*

QRS prolonged but NOT QT prolong - ANSWER ✔ Class IC: flecainide;
Propafenone

Verapamil, Diltiazem - ANSWER ✔ Class IV antiarrhythmics

Block Ca L-type channel
= *slow phase 4 depolarization*

AE of Verapamil and diltiazem - ANSWER ✔ Edema

, Constipation
Bradycardia

What antiarrhythmic is a *negative chronotropic *and what implications
does that have - ANSWER ✔ *Verapamil/Diltiazem *
*BBlock*
(DO NOT GIVE TOGETHER = Bradycardia)

Phenoxybenzamine - ANSWER ✔ irreversible a1/a2 antagonist

decrease max effect of NE
without affecting Km (affinity)

Where are B1 receptors OTHER THAN HEART - ANSWER ✔ JC
glomerulus

= B blockers also *inhibit renin*

Dobutamine - ANSWER ✔ *B agonist*
increase hr/contractility
via Gs-->*cAMP*

Isoproterenol - ANSWER ✔ *B agonist*
B1: increase CO and Pulse Pressure
B2: decrease PVR & diastolicBP

Esmolol, Atenolol - ANSWER ✔ *Selective B1 block *
= PROLONG PR interval
longterm use for LV-HF
only affects cardiac and renal (not bv)

What drugs prolong PR interval - ANSWER ✔ Esmolol
Atenolol

selective B1 block

Timolol - ANSWER ✔ non-selective BBlock

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