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BIOCHEMISTRY NBME EXAM QUESTIONS AND 100% CORRECT SOLUTIONS $9.49   Add to cart

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BIOCHEMISTRY NBME EXAM QUESTIONS AND 100% CORRECT SOLUTIONS

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  • Biochemistry NBME
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  • Biochemistry NBME

BIOCHEMISTRY NBME EXAM QUESTIONS AND 100% CORRECT SOLUTIONS What is the rate-limiting step of glycolysis? - ANSWER PFK, allosterically activated by F2,6BP Def in pyr kinase leads to... - ANSWER 2,3BPG, G6P elevation due to ^ PEP What steroid can be used to treat beta-bloc...

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  • September 6, 2024
  • 24
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • Biochemistry NBME
  • Biochemistry NBME
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ProfBenjamin
BIOCHEMISTRY NBME EXAM
QUESTIONS AND 100% CORRECT
SOLUTIONS


What is the rate-limiting step of glycolysis? - ANSWER ✔ PFK,
allosterically activated by F2,6BP

Def in pyr kinase leads to... - ANSWER ✔ 2,3BPG, G6P
elevation due to ^ PEP

What steroid can be used to treat beta-blocker overdose? -
ANSWER ✔ glucagon

Which form of aldolase is liver-specific? - ANSWER ✔ B

triose phosphate isomerase - ANSWER ✔ G3P <-> DHAP;
DHAP - component of glycerol phosphate shuttle

What TCA step makes GTP? - ANSWER ✔ succinate thiokinase

What TCA step makes FADH? - ANSWER ✔ succinate
dehydrogenase

What is the only membrane-bound enzyme in TCA? - ANSWER
✔ succinate dehydrogenase



ROugh ER - ANSWER ✔ Ribosomes

,near nucleus, protein synthesis, N-linked glycosylation

protien for anterograde transport - ANSWER ✔ COPII

cis-golgi

Protein for retrograde transport - ANSWER ✔ COPI
ER

Golgi - ANSWER ✔ post-translation modifications

what is is added to proteins to by designated to Lysosome?? -
ANSWER ✔ Mannose-6-phosphate

what mediates transport of protein to lysosome - ANSWER ✔
Clatherin
clatherin --> late endosome-? lysosome

singnal seguence - ANSWER ✔ chain of hydrophobic AA and
signal recognition directs it

signal peptidase - ANSWER ✔ cuts off signal sequence after is
translated through translocon

any failure can lead to cytosolic build up in cytosol

peroxisomes - ANSWER ✔ degrade fatty acids, amino acids
in brain and liver; cleaves 1C
generates H2O2

Verylong fatty acids (VLCFA) B-oxidation
Branched-chain fatty acid alpha-oxidation
Peroxisome synthetic processes

, catalase reaction - ANSWER ✔ degrades peroxide from
peroxisomes or uses for detox reaction

increase pathogencity

proteasome degrade ..? - ANSWER ✔ ubiquinated proteins

Actin - ANSWER ✔ smallest unit

G-actin monomers --> F actin
double helix
accessory protein= myosin

muscle contration

intermediate filaments - ANSWER ✔ cross linked by plectin

cytokeratin (epithelial cells), Vimentin (fibroblasts), Desmin
(muscle, GLial fibrillary acidic protein (glial cells), lamins (cell
nucleus)

microtubles - ANSWER ✔ polarize to organizing centers (-
towards the nucleus)

kinesin= anterograde transport
Dynein- retrograte transport

microtubules inhibitors - ANSWER ✔ mebendazole, Griseofulvin,
Colchicine, Vinca alkaloids, taxanes


What neurotransmitter stimulates release of epinephrine from
adrenal medulla? - ANSWER ✔ acetylcholine

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