CLINICAL MANIFESTATIONS: Icterus: __________________ progression as TSB rises
Cephalocaudal
Icterus: When will you see it in:
Face (__mg/dL)
Mid-abdomen (__mg/dL)
Soles of feet (__mg/dL)
What symptoms will you see at high levels of TSB?
-5
-15
, -20
-Lethargy and poor feeding at high TSB levels
RISK FACTORS FOR HYPERBILIRUBINEMIA: Maternal (5)
ABO or Rh incompatibility
Drugs (Oxytocin (Pitocin), Diazepam (Valium)
Diabetes
Age ≥ 25yrs
Breastfeeding
RISK FACTORS FOR HYPERBILIRUBINEMIA: Infant (9)
Infant
TSB in high/high intermediate risk zone
Prematurity
Poor intake
Delayed passage of stool
Increased enterohepatic circulation
Shorter RBC lifespan
Infection
Sibling with history of hyperbilirubinemia
FACTORS DECREASING RISK FOR HYPERBILIRUBINEMIA (4)
Gestational age ≥ 41 weeks
African
Exclusive bottle-feeding
Hospital discharge after 72 hours
low risk TSB zone
Newborns have __________ erythrocyte mass and __________ erythrocyte lifespan.
What is the hematocrit in adults vs newborns? What about the life span of the RBC?
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