Interbout interval - ✔message to make milk receeds without nipple stimulation
lengthening this interval decreases the amount of prolactin produced at the next feeding
Hormones during pregnancy - ✔progesterone blocks the receptor sites on alveolar cells
Delivery of placenta - ✔the sudden decrease in progesterone and estrogen allows prolactin to
slot into the receptor sites once infant begins suckling
within the first 2 hours
Mothers of premies - ✔initiation of milk expression before 1 hour resulted in
significantly more mik when measured on Day 7 and 42
Oxytocin - ✔hits receptors on myoepithelial cells stimulates contractions pushes milk out
of alveoli / contracts uterus
Triggers for oxytocin - ✔Conditioned response, conditioned milk ejection (Let Down reflex)
Oxytocin release mechanism (Nipple stretching with proper latch)
,Baby hand massage
Emotional / behavioral function of hormones - ✔aggression in terms of protection of baby
bonding
trust
Species with increased fat / protein and decreased water content - ✔infrequent feeds
Species with increased water content - ✔more frequent feeds
All mammal milk contains - ✔lactose
What triggers production of lactose in mammary cells - ✔prolactin
What does lactose do - ✔is the driving osmotic force to draw water into the milk
Different care patterns - ✔Associated with the type of milk composition
1. Nest / cache
2. Carry, follow, hibernate
Most rapidly developing organ in human newborns - ✔the
brain human milk = ideal for brain growth
Human Milk Composition - ✔Protein 1.2%
Fat 3.8%
CHO 7%
, Water 87.6%
One of the highest levels of lactose --> very diluted
Human care patterns - ✔milk composition is more suitable for
carrier society is more consistent with nesters
Stages of lactogenesis - ✔
Lactogenesis I (Secretory Differentiation) - ✔Placental hormones
Colostrum
Lactogenesis II (Secretory Activation) - ✔begins with the birth of the placenta
rapid decrease in progesterone
Transitional milk
Lactogenesis III (Galactopoesis) - ✔Comes from increase in prolactin via nipple stimulation
and frequent removal of milk
Mature milk
Preterm vs. Term Milk - ✔preterm appears to have different composition for first 5-7 wk
after delivery
higher in protein, fat, electrolytes
SGA / LGA had no impact on milk composition
Milk composition changes throughout lactation period - ✔Volume does not increase,
the composition changes to meet the increase caloric demands
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