100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
Previously searched by you
Cell Signaling in Cancer, DNA Repair and Cancer, Oncogenes and Cancer, Tumor Suppressor Genes, Cell Survival Pathways, Cancer Biology Syllabus Review| Qs & As Latest Update$12.99
Add to cart
Cell Signaling in Cancer, DNA Repair and Cancer, Oncogenes and Cancer, Tumor Suppressor Genes, Cell Survival Pathways, Cancer Biology Syllabus Review| Qs & As Latest Update
4 views 0 purchase
Course
Cell Signaling
Institution
Cell Signaling
Cell Signaling in Cancer, DNA Repair and Cancer,
Oncogenes and Cancer, Tumor Suppressor Genes, Cell
Survival Pathways, Cancer Biology Syllabus Review| Qs
& As Latest Update
Cell Signaling in Cancer, DNA Repair and Cancer,
Oncogenes and Cancer, Tumor Suppressor Genes, Cell
Survival Pathways, Cancer Biology Syllabus Review| Qs
& As Latest Update
Microsatellites - ✔✔Short, repetitive sequences of nucleotides scattered throughout the
human genome.
Mismatch repair (MMR) - ✔✔A system that recognizes and repairs misincorporations of bases
that arise during DNA replication.
Frameshift-mutated neoantigens - ✔✔Altered antigens resulting from frameshift mutations,
which can serve as predictors of sensitivity to immunotherapies.
Poly(ADP-ribose) polymerase (PARP) - ✔✔An enzyme involved in DNA repair and cell
death processes, often targeted in cancer therapy.
Nucleotide excision repair (NER) inhibitors - ✔✔Small molecules designed to target specific
proteins involved in the NER pathway, potentially improving the response to DNA-damaging agents
such as cisplatin.
1,25-dihydroxyvitamin D3 (1,25VD3) - ✔✔The active form of vitamin D3, which plays a role
in protecting DNA from UV damage and is involved in the nucleotide excision repair process.
ErbB family - ✔✔A family of receptor tyrosine kinases, including EGFR, that plays a role in
regulating DNA repair processes.
, IGF-1 Receptor (IGF-1R) - ✔✔A membrane-bound receptor that plays a role in regulating DNA
repair processes and is linked with the development of solid tumors.
Oncogene - ✔✔Mutated growth-controlling gene that promotes uncontrolled cell growth and
can lead to cancer.
Transfection - ✔✔The process of introducing DNA into cells, often used to detect oncogenes
in cancer cells.
Phosphate Buffer - ✔✔A solution used to maintain a stable pH when introducing DNA into
cells during transfection experiments.
Calcium Phosphate Crystals - ✔✔Crystals formed when DNA and calcium ions are added to
a phosphate buffer, facilitating the uptake of DNA fragments by cells.
Monolayer Culture - ✔✔A culture of cells in a single layer, often used in transfection experiments to
detect oncogenes.
Proto-oncogene - ✔✔A normal gene that can become an oncogene due to mutations, promoting
cell growth and development.
Growth Factors - ✔✔Proteins responsible for stimulating cell growth and development, regulated
by proto-oncogenes.
Growth Factor Receptors - ✔✔Proteins on the cell surface that bind to growth factors, initiating
the cell growth and division process.
Signal-Transduction Proteins - ✔✔Proteins that transmit signals within a cell, often involved in
the regulation of cell growth and division.
Transcription Factors - ✔✔Proteins that control the transfer of genetic information from DNA to
RNA, influencing gene expression and cell function.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller KenAli. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $12.99. You're not tied to anything after your purchase.
