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ONS Chemotherapy Administration questions and answers rated A+ 2024/2025
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ONS Chemotherapy Administration questions and answers rated A+ 2024/2025
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ONS Chemotherapy AdministrationWhat do alkylating chemotherapy capsules do? - ANSChemotherapy pills which might be
cellular cycle nonspecific, in order that they exert their outcomes in all phases of the cell
cycle. They immediately damage DNA to prevent cancer cells from reproducing. They
purpose breaks inside the DNA or go-linking in a procedure called alkylation, which reasons
the drug to interfere with DNA replication.
Neoadjuvant remedy - ANSa cancer treatment that precedes other primary treatment, such
as administering chemotherapy or radiation remedy to a patient before surgical procedure
adjuvant remedy - ANSTreatment of sickness with materials that assist or enhance the
motion of primary remedy (i.E. Surgical operation or radiation).
Induction treatment of leukemia - ANSThis segment of chemotherapy treatment (first
segment of treatment) typically is initiated inside the sanatorium due to its potential for
extreme side outcomes and complications from the severe, supposed myelosuppression that
ensues. The intention is to achieve a complete response.
Consolidation remedy - ANSThis treatment is accomplished to make sure the treatment
takes impact and reduces the hazard of a recurrence. This remedy is important due to the
fact leukemic cells that aren't clinically obvious, as via a CBC laboratory draw end result or
bone marrow biopsy evaluation, are nearly always nevertheless gift to some small degree
within the bone marrow.
Myeloablation remedy - ANSA technique in which the bone marrow purposely is obliterated
thru chemotherapy or radiation to put together for peripheral blood stem cell transplantation
or bone marrow transplantation. Myeloablation often is used to deal with blood (i.E., liquid)
malignancies, inclusive of leukemia or lymphoma.
Reinduction remedy - ANSThis treatment is used when a patient who correctly completed
induction and consolidation, but relapses months later.
Mixture therapy - ANSThis therapy reduces the likelihood of drug resistance due to the fact
the distinctive chemotherapy capsules have unique mechanisms of motion.
Cancer cells normally are heterogeneous; therefore, the impact of different mechanisms of
motion increases the quantity of most cancers cells killed at one time. The performance
visible by way of use of more than one chemotherapy marketers inside a routine provides a
synergistic impact.
Synergy - ANSWhen one chemotherapy drug enables every other one (given at the same
time) work higher, which include with leucovorin and five-fluorouracil while treating colon
cancer. Leucovorin increases the deadly impact that 5-fluorouracil has on cancer cells; in
other phrases, the cytotoxicity is potentiated.
, Whole reaction - ANSNo identifiable cancer presence via signs or symptoms for as a
minimum one month or longer
partial reaction - ANSThe measurable tumor is reduced through 50% for at least one month
without the improvement of new tumors.
Strong - ANSThe tumor is contracted via much less than 50%, or less than a 25% increase
in tumor increase happens.
Modern disease - ANSTumor growth of extra than 25% or development of recent most
cancers growth inside the frame
relapse or recurrence - ANSNew tumor increase after experiencing a entire response
What are the three approaches to measure a reaction to remedy? - ANSsurgical, imaging
and tumor marker tests
G stages chemotherapy unique purpose(s) - ANSprevent improvement of elements
necessary for mitosis.
G segment chemotherapy drug examples - ANSToposomerase I inhibitors (irinotecan,
topotecan and Topoisomerate II (doxorubicin , etoposide) and Blyomycin
M segment chemotherapy specific intention(s) - ANSprevent cell from going thru mitosis,
starting from metaphase arrest to microtubular disorganization
M phase chemotherapy drug examples - ANSPlant alkaloids (vincristine, vinblastine,
vinorelbine) and Taxanes (paclitaxel, docetaxel)
S segment chemotherapy specific goal(s) - ANSprevent the cellular from making DNA and/or
RNA with the aid of inhibiting biosynthesis of nucleic acids
S phase chemotherapy drug examples - ANSantifolates (methotrexate), antipyrimidines
(5-fu), and antipurines (hydroxyurea)
Non-precise cellular cycle drug examples - ANSalkylating agents (Cytoxan), anthracycline
antibiotics (doxorubin), Nitrosureas (lomustine) and Miscellaneous (cisplatin, dacarbazine,
mitomycin C)
Name some alkylating chemotherapy tablets. - ANSBusulfan
Carboplatin
Cisplatin
Cyclophosphamide
Ifosfamide
Melphalan
Oxaliplatin
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