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Fundamentals of Chemo and Immuno questions and answers rated A+ 2024/2025
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Fundamentals of Chemo and Immuno questions and answers rated A+ 2024/2025
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Fundamentals of Chemo and ImmunoAlkylating sellers - ANSCell cycle nonspecific (exert results in all levels of the cell cycle);
without delay damage DNA to prevent most cancers cells from reproducing
Cytoxan
(cyclophosphamide) - ANSAlkylating Agent
Vesicant info: can also motive irritation
Admin: IV, PO, Intraperitoneal
Contraindications & precautions: hypersensitive reaction, severe marrow depression,
impaired renal and hepatic dysfuction
Toxicity & negative: noticeably emetogenic, encourage aggressive hydration d/t capacity
acute hemorrhagic cystitis
Cisplatin - ANSAlkylating Agent
Vesicant data: vesicant >.5 mg/mL, irritant <.Five mg/mL
Admin: IV, Intraperitoneal
Contraindications & precautions: renal impairment, listening to loss, neuropathy
Toxicity & unfavorable: intense emetogenic (acute and behind schedule), acute renal failure,
anaphylactic-kind reaction
Carboplatin - ANSAlkylating Agent
Vesicant data: irritant
Admin: IV
Contraindications & precautions: myelosuppression (renal impairment patients), NV, allergy,
neuropathy, nephrotoxic
Toxicity & unfavorable: acute: anaphylactic-like reactions, embolism, stroke, and HF; critical:
hematologic toxicity, thrombocytopenia, leukocyte nadir
Oxaliplatin (Eloxatin) - ANSAlkylating Agent
Vesicant data: irritant with vesicant homes; treat like vesicant
Admin: IV
Contraindications & precautions: hx of allergy to oxali or other platinum compounds, women
of childbearing age avoid pregnancy d/t pregnancy risk cat. D, renal impairment,
breastfeeding sufferers
Toxic & detrimental: intense bloodless sensitivity, anaphylactic response, pulmonary fibrosis,
hepatotoxicity, fatigue, HA
Antimetabolites - ANSAct in the S segment; intrude with DNA synthesis; some with enzymes
that wished for DNA synthesis even as others are just like the regular DNA base pairs and
are falsely integrated into the DNA; DO NOT ALLOW THE CELL TO LEAVE THE S PHASE
Methotrexate - ANSAntimetabolite
Vesicant data: now not a vesicant or an irritant
Admin: PO, IV, IM, or intra-arterial
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