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ONS Chemotherapy Immunotherapy Certificate questions and answers rated A+ 2024/2025
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ONS Chemotherapy Immunotherapy Certificate questions and answers rated A+ 2024/2025
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ONS Chemotherapy ImmunotherapyCertificate
3 principal levels of cell department: - ANSInterphase
Mitotic segment
Cytokinesis
3 steps of interphase: - ANSFirst boom section (G1)
Synthesis phase (S section)
Second growth segment (G2)
4 levels of mitosis: - ANSProphase
Metaphase
Anaphase
Telophase
Innate immunity: - ANSNon-unique reaction, either:
1. Barrier (skin, mucous membranes, plant life of pores and skin/gut)
2. Cellular components (phagocytes, herbal killer cells, granulocytes, macrophages)
Adaptive immunity: - ANSFollows innate immunity if unsuccessful. Memory immunity,
inclusive of:
1. Humoral immunity (manufacturing of antibodies or immunoglobulins)
2. Cell mediated immunity (established upon T cells)
three. Regulatory T -cells (save you autoimmune reactions and restrict inflammatory
responses)
Define mutations - ANSVariations inside the nucleotide sequence of a gene
three foremost goals of treatment: - ANSCure
Control
Palliation
Define neoadjuvant therapy - ANSTreatment is given previous to surgery to decrease the
tumor
Define adjuvant remedy - ANSAdditional cancer remedy given after the primary treatment to
decrease the danger that the most cancers reoccur
Define conditioning/preparative therapy - ANSTreatments used to prepare a patient for stem
mobile transplantation
2 types of conditioning healing procedures: - ANSMyeloablative
Nonmyeloablative
, Define dose density - ANSDrug dose per unit of time
Define dose intensity - ANSAmount of drug brought over the years
How is relative dose depth (RDI) calculated? - ANSBy comparing the dose that the patient
ACTUALLY obtained to the deliberate dose of the standard regimen
How do alkylating sellers paintings? - ANSBy inflicting a destroy inside the DNA helix strand,
interfering with DNA replication and causing cellular dying
3 subcategories of alkylating sellers: - ANS1. Nitrogen mustards
2. Platinum-primarily based agents (do no longer own an alkyl institution however still termed
alkylating retailers as they work in addition)
three. Nitrosoureas
Most common subcategory of alkylating agents: - ANSNitrogen mustards
Common alkylating sellers: - ANSCyclophosphamide (Cytoxan)
Ifosfamide (Ifex)
Bendamustine (Treanda)
Common platinum-based agents: - ANSCisplatin (Platinol)
Carboplatin (Paraplatin)
What is precise about nitrosoureas sellers? - ANSAble to move the blood-mind barrier; may
be effective in treating some brain tumors
Common nitrosoureas sellers: - ANSCarmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with past due doses of: - ANSCarboplatin
These sellers are normally categorized as surprisingly emetogenic: - ANS1. Alkylating
dealers
2. Nitrosoureas
Pre-administration labs for alkylating dealers and nitrosoureas: - ANSBUN
Creatinine
CBC w/ diff
What is the drugs Mesna used for? - ANSBladder protectant with administration of
cyclophosphamide or ifosfamide
Instruct pts receiving ________ to keep away from exposure to cold air and ingesting cold
fluids for 3-4 days following treatment - ANSOxaliplatin
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