TEST BANK
Applied Pathophysiology for the Advanced Practice Nurse
Lucie Dlugasch, and Lachel Story
1st Edition
,Table of Contents
Chapter 01 Cellular Function 1
Chapter 02 Immunity 9
Chapter 03 Hematopoietic Function 15
Chapter 04 Cardiovascular Function 22
Chapter 05 Pulmonary Function 32
Chapter 06 Fluid, Electrolyte, and Acid-Base Homeostasis 40
Chapter 07 Urinary Function 46
Chapter 08 Reproductive Function 51
Chapter 09 Gastrointestinal Function 61
Chapter 10 Endocrine Function 69
Chapter 11 Neural Function 76
Chapter 12 Musculoskeletal Function 86
Chapter 13 Integumentary Function 96
Chapter 14 Sensory Function 102
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Test Bank - Applied Pathophysiology for the Advanced Practice Nurse, 1st Edition (Dlugasch, 2020)
Applied Pathophysiology for the Advanced Practice Nurse, First Edition
Lucie Dlugasch, Lachel Story
Chapter 1 Assessment Quiz
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Chapter 1 Cellular Function
Multiple Choice
1. Protein hormones and enzymes are stored in the _ , awaiting signals to be released into the
cell.
A) food vacuole
B) Golgi complex
C) rough endoplasmic reticulum
D) secretory vesicles
Ans: D
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
2. Low serum albumin levels (hypoalbuminemia) can cause edema because:
A) oncotic pressure increases.
B) oncotic pressure decreases.
C) osmotic pressure increases.
D) hydrostatic pressure decreases.
Ans: B
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
3. Neurotransmitters are packaged into vesicles and then fuse with the cell membrane for release. This is
an example of:
A) pinocytosis.
B) phagocytosis.
C) exocytosis.
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Test Bank - Applied Pathophysiology for the Advanced Practice Nurse, 1st Edition (Dlugasch, 2020)
Applied Pathophysiology for the Advanced Practice Nurse, First Edition
Lucie Dlugasch, Lachel Story
Chapter 1 Assessment Quiz
D) endocytosis.
Ans: C
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
4. What is a possible reason for increased risk for chromosomal abnormalities with older maternal age?
A) Ova meiosis is complete by the time a girl is born thereby making them less likely to divide properly.
B) The older ova are more likely to have errors during meiosis.
C) Older ova are more likely to have p53 gene mutations.
D) Ova are continuously produced thereby increasing the chance of creating defective ova.
Ans: B
Complexity: Moderate
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
5. DNA that is transmitted from parents to offspring mainly comes from the:
A) mitochondria.
B) nucleolus.
C) ribosomes.
D) nucleus.
Ans: D
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
6. A patient will be receiving stem cells obtained from a donor’s blood (allogenic transplant) for leukemia
(abnormal white blood cells). These stem cells are categorized as multipotent because they can make:
A) multiple types of cells in the body.
B) only white blood cells.
C) all types of blood cells.
D) differentiated cells that can become any cell.
Ans: C
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
7. During which phase of the cell cycle are there “checkpoints” where damaged DNA is fixed?
A) Interphase
B) Prophase
C) Metaphase
D) Anaphase
Ans: A
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Test Bank - Applied Pathophysiology for the Advanced Practice Nurse, 1st Edition (Dlugasch, 2020)
Applied Pathophysiology for the Advanced Practice Nurse, First Edition
Lucie Dlugasch, Lachel Story
Chapter 1 Assessment Quiz
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
8. A woman had a biopsy of a breast mass. Which of the following findings are considered precancerous?
A) Columnar metaplasia
B) Ductal atrophy
C) Atypical hyperplasia
D) Squamous hypertrophy
Ans: C
Complexity: Easy
Ahead: Cellular Adaptation and Damage
Subject: Chapter 1
Title: Cellular Function
9. A gene is one that produces an effect only in the homozygous state.
A) dominant
B) recessive
C) sex-linked
D) hemizygous
Ans: B
Complexity: Easy
Ahead: Genetic and Congenital Disorders
Subject: Chapter 1
Title: Cellular Function
10. Antioxidants found in food and vitamin supplements are thought to:
A) increase oxygenation.
B) improve absorption of beneficial minerals.
C) increase elimination of toxic chemicals.
D) counteract oxidative stress.
Ans: D
Complexity: Easy
Ahead: Cellular Adaptation and Damage
Subject: Chapter 1
Title: Cellular Function
11. Single nucleotide polymorphisms are best described as:
A) disease-causing genetic mutations.
B) variations on a single DNA base pair.
C) a number of copies on a particular gene that varies.
D) base pairs that alter gene expression.
Ans: B
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
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Test Bank - Applied Pathophysiology for the Advanced Practice Nurse, 1st Edition (Dlugasch, 2020)
Applied Pathophysiology for the Advanced Practice Nurse, First Edition
Lucie Dlugasch, Lachel Story
Chapter 1 Assessment Quiz
Title: Cellular Function
12. Which of the following are characteristic of malignant cells?
A) Anaplastic, proliferate, and nonfunctioning
B) Well differentiated and nonfunctioning
C) Anaplastic, encapsulated, and functioning
D) Some differentiation, evade apoptosis, and functioning
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
13. A patient has pancreatic cancer and has a RAS proto-oncogene mutation. This oncogene affects cells
by:
A) suppressing cellular growth and division.
B) turning off protein transcription.
C) allowing the cell to gain function such as proliferation.
D) destroying cellular repair mechanisms.
Ans: C
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
14. A mutation of the breast carcinoma 1 and 2 (BRCA1 and BRCA2) gene associated with cancer of the
breast and ovaries will result in cell:
A) loss of tumor suppressor function.
B) gain of tumor suppressor function.
C) accelerated hyperplasia.
D) increase in protein transcription.
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
15. Epigenetics is the field of science that evaluates:
A) changes in underlying DNA sequence.
B) single nucleotide polymorphism development.
C) copy number variant development.
D) mechanism of activation and deactivation of genes.
Ans: D
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
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Test Bank - Applied Pathophysiology for the Advanced Practice Nurse, 1st Edition (Dlugasch, 2020)
Applied Pathophysiology for the Advanced Practice Nurse, First Edition
Lucie Dlugasch, Lachel Story
Chapter 1 Assessment Quiz
16. Dysplasia of epithelial cells sometimes results from:
A) excessive sodium intake.
B) chronic irritation or inflammation.
C) increased enzyme synthesis.
D) apoptosis.
Ans: B
Complexity: Easy
Ahead: Cellular Adaptation and Damage
Subject: Chapter 1
Title: Cellular Function
17. Which of the following types of gangrene is usually a result of arterial occlusion?
A) Necrosis
B) Dry
C) Wet
D) Gas
Ans: D
Complexity: Easy
Ahead: Cellular Adaptation and Damage
Subject: Chapter 1
Title: Cellular Function
18. A metastatic tumor is one that:
A) needs an adequate blood supply to survive.
B) shows slow expansion and well-differentiated cells.
C) remains active to survive.
D) invades deeply into the tissue where it arose.
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
19. An example of a test that is used for cancer screening (asymptomatic test) is:
A) cytology (pap) smear.
B) endometrial (uterine) biopsy.
C) magnetic resonance imaging of the lungs.
D) thyroid cancer blood tests.
Ans: A
Complexity: Easy
Ahead: Neoplasms
Subject: Chapter 1
Title: Cellular Function
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Test Bank - Applied Pathophysiology for the Advanced Practice Nurse, 1st Edition (Dlugasch, 2020)
Applied Pathophysiology for the Advanced Practice Nurse, First Edition
Lucie Dlugasch, Lachel Story
Chapter 1 Assessment Quiz
20. Enzymes that use oxidation to convert food materials into energy are found in sausage-shaped
structures called:
A) secretory vesicles.
B) ribosomes.
C) mitochondria.
D) Golgi apparatus.
Ans: C
Complexity: Easy
Ahead: Basic Cell Function and Structure
Subject: Chapter 1
Title: Cellular Function
21. _ syndrome occurs in males when there is an extra X chromosome.
A) Triple X
B) Turner
C) Klinefelter
D) XYY
Ans: C
Complexity: Easy
Ahead: Genetic and Congenital Disorders
Subject: Chapter 1
Title: Cellular Function
22. A couple has three offspring: one child has an autosomal dominant disease trait and the other two
children do not have the trait. The father is affected by the autosomal dominant disease, but the mother
does not have the disease gene. What is the recurrence risk of this autosomal dominant disease for their
next child?
A) 50%
B) 33%
C) 25%
D) Unable to determine
Ans: A
Complexity: Easy
Ahead: Genetic and Congenital Disorders
Subject: Chapter 1
Title: Cellular Function
23. What is the diagnosis of a 13-year-old female who has a karyotype that reveals an absent
homologous X chromosome with only a single X chromosome present? Her features include a short
stature, widely spaced nipples, reduced carrying angle at the elbow, and sparse body hair.
A) Down syndrome
B) Cri du Chat
C) Fragile X syndrome
D) Turner syndrome
Ans: D
Complexity: Easy
Ahead: Genetic and Congenital Disorders
Subject: Chapter 1
Title: Cellular Function
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