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Inflammation NURS 5315 Exam Questions and Answers 2024( A+ GRADED 100% VERIFIED).
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Inflammation NURS 5315 Exam Questions and Answers 2024( A+ GRADED 100% VERIFIED).
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Inflammation NURS 5315cellular injury leads to: (5) - ANS 1. coagulation cascade activation
2. Kinin system activation
3. Mast cell degranulation
4. Complement cascade activation
5. chemotactic factors released
Coagulation cascade activation leads to (4) - ANS fibrin mesh containing the injury
traps microorganisms to prevent spread
stops bleeding
plasmin-activates complement and kinin system
Kinin system activation leads to (4) - ANS Bradykinin released:
pain
vasodilation/permeability
chemotaxis
Complement cascade activation leads to (5) - ANS MAC-lysis of bacteria
C2B--increased vasodilation and permeability
C3a/C5a/C4a--triggers mast cell degranulation
C5a attracts neutrophils
C3b enhances opsonization
C2B does what?
and is apart of what chain - ANS increases vasodilation and permeability
complement cascade activation
MAC does what?
and is it a part of what chain? - ANS lysis of bacteria
complement cascade activation
C5a does what?
, and is a part of what chain? - ANS Attracts neutrophils
complement cascade activation
C3b does what?
and is a part of what chain? - ANS Enhances opsonization
complement cascade activation
Chemotactic factors released leads to what? - ANS attraction of neutrophils, eosinophils and
monocytes
phagocytosis (leads to WBC death/rupture)
-Activates complement, kinin and coagulation cascade
monocytes present antigens and activate T/B cell immunity--release cytokines Il 1, IL 6, TNF
and growth factors
monocytes present antigens and activate T/B cell immunity--release cytokines Il 1, IL 6, TNF
and growth factors
happens in which chain - ANS Chemotactic factors released
Mast cell degranulation leads to: (5) - ANS Histamine
cytokines
leukotrienes
prostaglandins
platelet activating factor
histamine does what? - ANS vasodilation/increased permeability
increased blood flow to site
local swelling/erythema
cytokines do what (in mast cell degranulation) - ANS TNF--leukocyte emigration, inc
permeability
IL 13--chemotaxis, B cell proliferation and antibody production
IL4--B Cell proliferation and antibody production
Which interleukin is elevated early in inflammation? - ANS IL4
Which interleukin is elevated later in inflammation? - ANS IL 13
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