Class notes
Biol 141 Proteins Condensed Notes
- Course
- BIOL 141 BIO 141
- Institution
- Emory University
Comprehensive and detailed Protein Condensed Notes for Biol 141. *Essential!! *For you, at a price that's fair enough!!
[Show more]
Content preview
Proteinso Amino Acids and Polymerization
Structure
H- hydrogen atom
NH2- amino functional group
COOH2- carboxyl functional group
Distinctive R group (side chain)
How they behave in water
They ionize
o Causes the amino group to act as a base (forms NH3+)
o The carboxyl group acts as acid (COO+)
Side chains
Represents the part of the amino acid core structure that each of the 20
different amino acids unique
Functional groups affect reactivity
o Amino acids with (SH) in the side chain can form (S-S) disulfide
bonds that help link different parts of large proteins
, o Some functional groups only have H and C atoms, which rarely
participate in chemical reactions (mean they depends primarily on
their size and shape)
Polarity and Charge of R-groups Affect Solubility
o Hydrophilic
Polar and electrically charged R-groups
Dissolve easily in water
Serine, Threonine, and Cysteine
Acidic: aspartic acid, glutamic acid
Basic: lysine, arginine, histidine
o Hydrophobic
Non-polar, lack charge, highly electronegative
Coalesce in solution
Glycine, Alanine, and Valine
Proline, tryptophan, phenylalanine
o 3 things to look at
Does the R-group have – charge
If yes, then its acidic and has lost proton
Does the R-group have + charge
If yes, then its basic and has accepted proton
If the R-group has NO charge, does it have an O atom?
If yes, then the highly electronegative O will form a
polar covalent bond, making it uncharged polar
If NONE of the above are true
It is a nonpolar amino acid
How amino acids link to make proteins
o The C-N covalent bond that forms from condensation is a PEPTIDE
BOND
o Peptide bonds
Forms in ribosomes
Usually stable
C-N form a double bond
C-O single bond
Have some of the same characteristics as double bonds
Planar
Limiting movement of the atoms that are in the
peptide bond
R-group orientation
The side chains of the residue extend to backbone,
interact with others and water
Directionality
Amino group on one end of the backbone and a
carboxyl group on the other
N-terminus (amino terminus)
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller anyiamgeorge19. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $9.99. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75632 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now