PSIO 303 Exam 3 Practice Questions and Answers (100% Pass)
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Course
PSIO 303
Institution
PSIO 303
PSIO 303 Exam 3 Practice Questions and
Answers (100% Pass)
The earliest defects that arise with Metabolic Syndrome are
impaired glucose tolerance (IGT) and hyperinsulinemia -
Answer️️ -False
All individuals who develop Metabolic Syndrome will eventually
develop type 2 diabetes - Answer️...
PSIO 303 Exam 3 Practice Questions and
Answers (100% Pass)
The earliest defects that arise with Metabolic Syndrome are
impaired glucose tolerance (IGT) and hyperinsulinemia -
Answer✔️✔️-False
All individuals who develop Metabolic Syndrome will eventually
develop type 2 diabetes - Answer✔️✔️-False
Adipose tissue stores lipid, but also has an endocrine function in
the release of cytokines and other types of chemical messengers
(hormones, etc). - Answer✔️✔️-True
The microvascular complications (e.g. retinopathy) of the Metabolic
Syndrome start developing during the phase of compensatory
hyperinsulinemia. - Answer✔️✔️-False
When it comes to essential hypertension in Metabolic Syndrome, it
is suggested that ___ and ___ may be responsible for the
development of this core component by increasing central
sympathetic outflow, causing peripheral vasoconstriction, and
more. - Answer✔️✔️-Insulin resistance ; hyperinsulinemia
What type of "body shape" reflects a greater proportion of visceral
adiposity, and thus represents a great risk group for other
components of Metabolic Syndrome? - Answer✔️✔️-Apple
C. It produces glucose de novo from various substrates in a process
known as glycogenolysis.
D. It is the first organ to process nutrients fro the intestines via the
hepatic-portal circulation.
E. It stores glucose in the form of glycogen. - Answer✔️✔️-A, D, E are
correct
The magnitude of ultimate intracellular response initiated by ligand
binding to plasma membrane receptors is linearly related to the
number of receptors bound by the ligand. - Answer✔️✔️-False
Activation of nuclear receptors induces changed in cellular function
through the production of 2nd messengers. - Answer✔️✔️-False
Select the following statements about the G-protein coupled
receptors (GPCRs) that are true.
A. Activation of the alpha subunit of the G-protein occurs when
GTP is hydrolyzed to GDP
B. The beta and gamma subunits of G-proteins interact with
adenylate cyclases in order to produce cAMP
C. cAMP (produced after Galphas-protein activation) acts as a 2nd
messenger within the cell
D. Activation of the PLC (by Gq-protein activation) results in the
production of IP3 and DAG, which have effects on Ca2+ levels and
PKC activity, respectively. - Answer✔️✔️-C and D are correct
Where is the GLUT-2 glucose transport isoform highly expressed? -
Answer✔️✔️-Liver and intestine
Which one of the following statements is NOT true of skeletal
muscle glucose uptake and its underlying mechanisms.
A. Nitric oxide can be stimulated to diffuse to the smooth muscle
cells and cause relaxation and vasodilation.
B. Insulin action on the vascular endothelium of capillaries
perfusing skeletal muscle includes decreasing the number of
capillary contacts on the skeletal muscle.
C. Nitric oxide promotes the delivery of glucose and causes
leakiness in the endothelium of the capillaries in contact with the
muscle.
D. Insulin can act on the endothelial cells in the capillary bed of the
skeletal muscle tissue to activate nitric oxide synthase (eNOS),
leading the nitric oxide production. - Answer✔️✔️-B and C are correct
Insulin can act on the endothelial cells in the arterioles supplying
blood to the skeletal muscle tissue to activate nitric oxide synthase
(eNOS), leading to nitric oxide production. - Answer✔️✔️-True
Impairments in both delivery of glucose to the skeletal muscle cell
and the transport of glucose into the cell in response to insulin
action contribute to insulin resistance - Answer✔️✔️-True
Only IRS-1 will be affected by the up-regulation of PKC theta by free
fatty acids (FFAs) - Answer✔️✔️-False
4
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