Seizure - Answer✔️✔️-excessive or not enough firing of neurons
Shelia has tetanus - Answer✔️✔️-- women is bending back too much glycine
- blocking release of glycine from axon terminals but blocking preventing
combinations of presynpatic
- when her back is breaking she is able to feel the pain - she is fully aware
- she was given Curare because it paralyze her so she wont break her back
Q) Why does this process not cause paralysis? - Answer✔️✔️-Ion channels
that glycine control are chloride - lose inhibitor of a neuron will cause
excitation which causes muscle movement
Q) A drug takes place mostly where? - Answer✔️✔️-Synapse
Q) What is outside layer of the Synapse? - Answer✔️✔️-Calcium channels
Q_) After an action potential efflux of what ion establishes the membrane
potential? - Answer✔️✔️-Potassium
- gated voltage channels
- sodium and action potential are independent
Don - A retired accountant developed tremor and slowing of movements
and was diagnosed with Parkinson's disease at age 67. His neurologist
prescribed levodopa to restore dopamine levels. A couple of years later,
motor symptoms start to fluctuate and the dopamine receptor agonist
ropinirole was added to his treatment.
A few months later, he developed a strong interest in gambling, first
buying lottery tickets and then visiting a casino almost every day. He
concealed his gambling activity until he has lost more than $100,000.
He came for a consultation 5 weeks ago, and ropinirole was replaced with a
monoamine oxidase inhibitor drug. He now reports his interest in
gambling has disappeared. - Answer✔️✔️-Dopamne drug which impacts
what you get addicted to and controls motor functions
- dopamine impacts the midbrain
- impacts learning and reinforcement
Receptor: Ionotropic - Answer✔️✔️-Where a ligand is going to bind; diret
effect
Antagonist - Answer✔️✔️-- prevents a receptor from being activated by
other ligands
- competitive: who ever gets there first gets the spot (between drug and
natural ligand)
What kind of drug is most common because it is most complicated? -
Answer✔️✔️-Noncompetitive antagonist
Class of Neurotransmitters: Amino Acids - Answer✔️✔️-- Gluamate
- Asparate
- Glycine
- GABA
Class of Neurotransmitters: Monoamines - Answer✔️✔️-- Catecholamines
- Dopamine
- Epinephrine
- Norepinephrine
- Indolamines
- Serotonin
Class of Neurotransmitters: Soluble Gases - Answer✔️✔️-- Nitric Oxide
- Carbon monoxide
Class of Neurotransmitters: Acetycholine - Answer✔️✔️-Acetycholine
3
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