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UAMS IMMUNOLOGY EXAM 5 REVIEW QUESTIONS & ANSWERS 2024/2025 $7.99   Add to cart

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UAMS IMMUNOLOGY EXAM 5 REVIEW QUESTIONS & ANSWERS 2024/2025

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UAMS IMMUNOLOGY EXAM 5 REVIEW QUESTIONS & ANSWERS 2024/2025 Virus - ANSWERSSubmicroscopic particles; obligate intracellular parasites that require living cells to replicate Genome - ANSWERSEither RNA or DNA Capsid - ANSWERSprotein shell that encloses the viral genome Capsomere - ANSWERS...

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  • August 28, 2024
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  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • UAMS IMMUNOLOGY
  • UAMS IMMUNOLOGY
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UAMS IMMUNOLOGY EXAM 5 REVIEW
QUESTIONS & ANSWERS 2024/2025
Virus - ANSWERSSubmicroscopic particles; obligate intracellular parasites that require living cells to
replicate



Genome - ANSWERSEither RNA or DNA



Capsid - ANSWERSprotein shell that encloses the viral genome



Capsomere - ANSWERSsubunit of the capsid



Neucleocapsid - ANSWERScapsid with enclosed genome



Viral envelope - ANSWERSA membrane that cloaks the capsid that in turn encloses a viral genome.



Virion - ANSWERSa fully formed virus that is able to establish an infection in a host cell



Viral infection mechanism - ANSWERSAttachment > Penetration > Uncoating > Transcription > Translation
> Assembly > Budding > release



Classification of viruses - ANSWERSType of nucleic acid and configuration; viral replication, virion



Virus major routes into the body - ANSWERSMucous membranes, skin, inhalation



Laboratory detection of viruses - ANSWERSserology, electron microscopy, cytology, antigen detection,
cell culture, and molecular testing



Viral serology - ANSWERSdetection of patient antibodies to the virus. IgM tests detect recent infections

, Viral electron microscopy - ANSWERS-Viruses are sufficiently unique in a structure that they can be
differentiated into families as genes



viral cytology - ANSWERSTznack prep; FIA



Tznack Prep - ANSWERSHost cells are stained with dyes and observed for characteristic morphology



FIA - ANSWERSStaining is more sensitive that dye based staining



Viral antigen detection - ANSWERSImmunofluorescence; enzyme immunoassay, latex agglutination, and
rapid immunochromatographic membrane assay



optical immunoassay - ANSWERSSilicon wafers coated with ABY + Virus; produce refection change in
wafer



Hemadsorption - ANSWERSViral AGNs that agglutinate RBCs, Guinea pig RBCs + infected cells = ring RBCs
around infected cells; viruses ID'ed using fluorescent-labeled ABY



Viral antigen detection methods are used for - ANSWERSscreening; have lower sensitivities; negative
results should be confirmed with cell culture, IFA, or molecular testing



Viral cell culture - ANSWERSGold standard; requires living cells that are kept moist and supplied with
nutrients by keeping them continuously immersed in cell culture medium



Primary cell culture - ANSWERSUsually tissue from animal PMK; divides only once or twice



diploid cell culture - ANSWERSDivide but limited to 50 generations; uses human neonatal lung or rabbit
kidney



Continuous cell culture - ANSWERSCapable of indefinite passages

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