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UAMS Immunology Exam 4 Questions & Answers 2024/2025 $7.99   Add to cart

Exam (elaborations)

UAMS Immunology Exam 4 Questions & Answers 2024/2025

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UAMS Immunology Exam 4 Questions & Answers 2024/2025 transient hypogammaglobulinemia of infancy X linked Bruton's agammaglobulinemia IgA deficiency common variable immunodeficiency (CVI) - ANSWERSlist the primary deficiencies of the B cell system. DiGeorge anomaly purine-nucleoside phos...

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  • August 28, 2024
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  • 2024/2025
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  • Questions & answers
  • UAMS Immunology
  • UAMS Immunology
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UAMS Immunology Exam 4 Questions &
Answers 2024/2025

transient hypogammaglobulinemia of infancy

X linked Bruton's agammaglobulinemia

IgA deficiency

common variable immunodeficiency (CVI) - ANSWERSlist the primary deficiencies of the B cell system.



DiGeorge anomaly

purine-nucleoside phosphorylase (PNP) deficiency - ANSWERSlist the cellular immunity deficiencies.



severe combined immunodeficiency (SCID)

wiskott-aldrich syndrome (WAS)

ataxia-telangiectasia (AT) - ANSWERSlist the combined deficiencies of cellular and humoral immunity.



oxidative metabolism disorders (chronic granulomatous dz and myeloperoxidase deficiency)

leukocyte adhesion molecule deficiency - ANSWERSlist the two types of neutrophil function defects.



secondary immune deficiency - ANSWERSwhat is an abnormality due to another disorder, infection, or
treatment?



malignancies: hodgkins dz and lymphoma, leukemia, myeloma, macroglobulinemia

infections: bacterial, viral, protozoan, helminthic, fungal; most prominent among these is AIDS

other conditions: burns, diabetes, malnutrition, surgical trauma, renal malfunction, aging, alcoholic
cirrhosis - ANSWERSlist the secondary immune deficiencies.



transient hypogammaglobulinemia of infancy - ANSWERSwhat is the deficiency?

, prolonged low Ig levels, children have problems with infections, and delay in Ig levels attributed to poor
T cell help



X linked brutons agammaglobulinemia - ANSWERSwhat is the deficiency?



development of B cell blocked at pro-B cell to pre-B cell, deficient in tyrosine kinase, small/absent and
abnormal lymphoid tissue, persitent beyond 2 years of age, treat with Ig preparation



IgA deficiency - ANSWERSwhat is the deficiency?



most common congenital immunodeficiency, most asymptomatic, anti-antibodies produced by some
(cause anaphylaxsis following transfusion), replacement therapy not useful



common variable immunodeficiency (CVI) - ANSWERSwhat is the deficiency?



normal # of B cells, cannot differentiate into Ig producing cells, usually in 20s and 30s, manifestations
(malabsorption/diarrhea, malignancies, autoimmune disorders), IgG & IgA deficient, recurrent infections,
treat with Ig preparations and antibiotics



DiGeorge anomaly - ANSWERSwhat is the deficiency?



missing portion of chromosome 22, embryonic development defect in thymus and other organs,
insufficient # of mature T cells, treat with fetal thymus and BM transplant and thymic hormones



purine-nucleoside phosphorylase - ANSWERSwhat is the deficiency?



defect in enzyme involved in purine metabolism, # of T cells decrease as toxic purine metabolite
accumulates, humoral immunity OK



severe combined immunodeficiency (SCID) - ANSWERSwhat is the deficiency?

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