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Exam (elaborations)

NR 507 FINAL EXAM 2024 with verified ANSWERS

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  • Course
  • NR 507 ADVANCED PATHOPHYSIOLOGY
  • Institution
  • NR 507 ADVANCED PATHOPHYSIOLOGY

NR 507 FINAL EXAM 2024 with verified ANSWERS

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  • August 27, 2024
  • 19
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NR 507 ADVANCED PATHOPHYSIOLOGY
  • NR 507 ADVANCED PATHOPHYSIOLOGY
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NR 507 FINAL EXAM 2024 with verified
ANSWERS

Ischemic penumbra - .......🔷ANSWERS🔶......✔✔ ischemic but not infarcted (salvageable) tissue.
Peri-infarct tissue.

-no structural damage



Dermatomes - .......🔷ANSWERS🔶......✔✔ area of the skin that is mainly supplied by branches of a
single spinal sensory nerve root. These spinal sensory nerves enter the nerve root at the spinal cord,
and their branches reach to the periphery of the body.



Substance release at the synapse - .......🔷ANSWERS🔶......✔✔ Acetylcholine- Excitatory or
inhibitory- alzheimers



Norepi- Excitatory or inhibitory- sleep/wake cycle, SYNS transmission



Dopa- Excitatory (h1 and h2 receptors) and inhibitory (H3 receptors). parkinson disease



Spondylolysis - .......🔷ANSWERS🔶......✔✔ structural defect (degeneration, fracture, or
developmental defect) in the pars interarticularis of the vertebral arch (the joining of the vertebral
body to the posterior structures). The lumbar spine at L5 is affected most often.

-Heredity

-Other congenital spinal defects



motor and sensory areas of the brain - .......🔷ANSWERS🔶......✔✔ Parietal lobe- major area for
somatic sensory input, located along the postcentral gyrus. which is adjacent to the primary motor
area in the precentral gyrus.



Primary motor area (Brodmann area 4)- located along the precentral gyrus forming the primary
voluntary motor area (homunculus) (little man).

,Association fibers provide communication between sensory and motor



Cerebral infarction - .......🔷ANSWERS🔶......✔✔ ischemic- white infarct (affected area is pale and
soft 6-12 hours after). necrosis appears by 48 to 72 hours.



Infiltration of macrophages and phagocytosis of necrotic tissue. necrosis resolves around the 2nd
week. glial scarring.



excitotoxins - .......🔷ANSWERS🔶......✔✔ Toxins (usually amino acids) that overstimulate
glutamate release and cause neuron suicide.



Agnosia - .......🔷ANSWERS🔶......✔✔ the inability to recognize familiar objects.



-tactile/spatial-parietal lobe

-Gerstmann syndrome (loss of spatial orientation of fingers, body, sides and #s)- L angular gyrus
(Parieral)

-Object- Temporo-occipital area

-Associated with CVAs



Subarachnoid hemorrhage - .......🔷ANSWERS🔶......✔✔ Bleeding into the subarachnoid space,
where the cerebrospinal fluid circulates.

-ruptured intracranial aneurysm/trauma

-IICP/irritates meningeal tissues/produces inflammation, blood coats nerve roots, impairs CSF
circulation

-compensatory increase in SBP



Meningitis - .......🔷ANSWERS🔶......✔✔ Bacterial- Meningococcus and S. pneumococcus bacteria
are most common



Viral- Specific pathogen cannot be found in CSF

, Prostate cancer prevention - .......🔷ANSWERS🔶......✔✔ -Eat a low fat diet

- Slow growing cancer so DRE and PSA testing prevents



BPH and the urinary system - .......🔷ANSWERS🔶......✔✔ - Chronic inflammation

-Bladder outflow obstruction

-Urge to pee often

-delay in starting stream

- Decreased force of stream

-Urinary retention/ overflow incontinence (late sign)

Complications: Hematuria, infections, bladder calculi, retention, hydronephrosis, renal insufficiency



Cause of respiratory Alkalosis - .......🔷ANSWERS🔶......✔✔ - fever

-anemia,

-anxiety, panic

-thyrotoxicosis

-hyperventilation



buffer molecules - .......🔷ANSWERS🔶......✔✔ -Plasma- Bicarbonate-carbonic acid and HGB.

-Intracellular- Phosphate and protein

Renal- Ammonia and Phosphate



Cushing's disease - .......🔷ANSWERS🔶......✔✔ - Excess endogenous secretion of ACTH
(Corticotropin).

-from a pituitary adenoma or by an ectopic secreting non pituitary tumor such as small cell
carcinoma of the lung.or adrenal tumor (rare)



- HYPERnatremia, HYPERtension, INCREASED blood volume, HYPOkalemia, HYPERglycemia,
weight gain, thin hair, moon face, easy bruising, buffalo hump, protein wasting

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