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Exam (elaborations)

NR 507 midterm exam questions with answers

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  • Course
  • NR 507 ADVANCED PATHOPHYSIOLOGY
  • Institution
  • NR 507 ADVANCED PATHOPHYSIOLOGY

NR 507 midterm exam questions with answers

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  • August 27, 2024
  • 21
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NR 507 ADVANCED PATHOPHYSIOLOGY
  • NR 507 ADVANCED PATHOPHYSIOLOGY
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NR 507 midterm exam questions with
answers

Hypersensitivity: Type 1 - .......🔷ANSWERS🔶......✔✔ -Mediated IgE

-inflammation due to mast cell degranultion

-anaphylactic, asthma, hay fever

treatment: epinephrine



Hypersensitivity: Type 2 - .......🔷ANSWERS🔶......✔✔ -Cytotoxic reaction: tissue specific

-binds to the antigen ON THE CELL SURFACE

-macrophages are primary effectors cells involved

cause tissue damage or alter function



Hypersensitivity 2 - .......🔷ANSWERS🔶......✔✔ -Graves Disease (hyperthyroidism) -alters function
not destroy

-blood transfusions reaction- transfused erythrocytes are destroyed by agglutination or lysis

-drug allergies

-hemolytic anemia



Hypersensitivity: type 3 - .......🔷ANSWERS🔶......✔✔ -Not organ specific

-antibody binds to soluble antigen OUTSIDE THE CELL SURFACE that was released into the blood
or bodily fluids, and the complex is then deposited in the tissues



Hypersensitivity: Type 3 - .......🔷ANSWERS🔶......✔✔ -rheumatoid arthritis

-Systemic Lupus Erythematosus (SLE)

-Raynaud's



Hives (urticaria) - .......🔷ANSWERS🔶......✔✔ Hypersensitivity Type 1

,First responders to innate the immune system - .......🔷ANSWERS🔶......✔✔ Neutrophils



Allergic contact dermatitis - .......🔷ANSWERS🔶......✔✔ Hypersensitivity Type IV



Type 2 cytotoxic hypersensitivity mediated by: - .......🔷ANSWERS🔶......✔✔ -IgG IgM

-macrophages are primary effort cells

-



Serum Sickness - .......🔷ANSWERS🔶......✔✔ type 3 hypersensitivity



Hypersensitivity IV, - .......🔷ANSWERS🔶......✔✔ -is more of a delayed immune response.

-mediated T-cells attack tissue directly (no antibodies)



Autoimmune - .......🔷ANSWERS🔶......✔✔ -diseases in which the body makes antibodies directed
against its own tissues

-



Primary immunodeficiency - .......🔷ANSWERS🔶......✔✔ -Genetic; inherited

-result of single gene defects

-B and T cell deficiencies



secondary immunodeficiency - .......🔷ANSWERS🔶......✔✔ -acquired



Common cause of secondary immunodeficiency - .......🔷ANSWERS🔶......✔✔ Malnutrition



Most patients diagnosed with SLE will have a positive ? - .......🔷ANSWERS🔶......✔✔ antinuclear
antibody (ANA)

, SLE (lupus) - .......🔷ANSWERS🔶......✔✔ -Facial rash

-vasculitis

- tissue inflammation



Renal disease associated with autoimmunity? - .......🔷ANSWERS🔶......✔✔ Glomerulonephritis



Sjogren's syndrome - .......🔷ANSWERS🔶......✔✔ Inflammation in salivary and lacrimal glands



SLE - .......🔷ANSWERS🔶......✔✔ Autoantibodies and auto-active t-cells against DNA and
nucleoprotein



Sjögren's syndrome immune changes: - .......🔷ANSWERS🔶......✔✔ Autoantibodies and auto-
reactive t-cells against apoptotic cells



rheumatoid arthritis manifestations: - .......🔷ANSWERS🔶......✔✔ Joint inflammation, stiffness,
pain, loss of range of motion



Rheumatoid Arthritis immune changes: - .......🔷ANSWERS🔶......✔✔ T-cells and B cells against
joint associated antigens



MS manifestations - .......🔷ANSWERS🔶......✔✔ Formation of sclerotic plaque in the brain, leads to
Muscle weakness and ataxia



MS immune changes - .......🔷ANSWERS🔶......✔✔ T-cells against brain antigens



___ measures the average size of RBCs - .......🔷ANSWERS🔶......✔✔ MCV



Anemia occur by... - .......🔷ANSWERS🔶......✔✔ -impaired RBC production

-excessive blood loss

- increased RBC production

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