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MMSC407 Exam 1 (113 questions already graded A+).
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MMSC407 Exam 1 (113 questions already graded A+).
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MMSC407 Exam 1 (113questions already
graded A+)
Test request protocol, patient prep and
identification, specimen collection and transport,
specimen storage; lab must provide instruction for
these - answer What are pre analytical variables?
Calibration, documentation of analytical protocol
and procedures, monitoring equipment and
materials, prep/storage of reagents, daily/monthly
preventative maintenance - answer What are
analytical variables?
Recording and reporting of data to physician in
appropriate time interval; QC doesn't detect these
types of variations!! - answer What are post-
analytical variables?
Pre-analytical, analytical, and post-analytical -
answer What are the 3 phases of clinical
laboratory quality assurance?
,Control range - answer specific combination of
controls and control limits
Acceptable control range - answer +/- 2 standard
deviations from the mean
analytical measurement range - answer range of
analyte concentrations that a method can directly
measure without any dilution, concentration or
other pretreatment
clinically reportable range - answer range of an
assay over which the concentrations of an analyte
can be measured with acceptable accuracy and
precision
reference range - answer range of acceptable
numbers, vary based on age, gender, race etc.
calculation required - answer control range =
mean +/- 2 standard deviations; run the same QC
lot for at least 20 days
Control vs. calibrators - answer Calibrators are
used to measure the accuracy of test results and
often referred to as 'standardized samples'. Quality
controls are used to monitor the performance of
, tests and procedures over time, and to adjust or
improve the accuracy of test results
Random error - answer change in precision as
reflected by a change in standard deviation
distribution
Associated w pipetting errors, variations in
technique, mixing sample w reagent, and
temp/timing instability
Referred to as unpredictable variation because it
cannot be completely identified or controlled (due
to chance)
systematic error - answer change in accuracy as
reflected by a change in the mean
Associated w calibration probs, contaminated
standards, improper calibrator/reagent prep,
failing instrumentation
Referred to as predictable variation because it's
constant
Mean - answer The average of a set of numbers
Median - answer Middle number
Mode - answer most frequently occurring number
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