Ages 5-11: SABA PRN + High-dose IGC + LABA +
Oral glucocorticoids
Ages 12-Adult: High-dose IGC + LABA + Oral glucocorticoids and Consider omalizumab
for patients with allergies
,Advantages of Inhaled Route of Anti-Asthma Drugs - CORRECT ANSWER: (1)
therapeutic effects are enhanced by delivering drugs directly to their site of action, (2)
systemic effects are minimized, and (3) relief of acute attacks is rapid.
Alosetron (Lotronex) - CORRECT ANSWER: approved only for treating women with
severe IBS-D that has lasted for 6 months or more and has not responded to
conventional treatment.
Alosetron Black Box Warning - CORRECT ANSWER: Can cause ischemic colitis
(intestinal damage secondary to reduced blood flow)
Alosetron CONTRAINDICATIONS/PRECAUTIONS - CORRECT ANSWER:
Contraindicated for clients who have chronic constipation, history of bowel obstruction,
Crohn's disease, ulcerative colitis, impaired intestinal circulation, diverticulitis, or
thrombophlebitis.
Antacid and Drug Interaction - CORRECT ANSWER: -can influence affects of other
drugs (ranitidine, cimetidine, sucralfate)
-interactions can be minimized by providing a gap of 1 hour between taking antacids
and these other drugs.
Antacid and Sodium Loading - CORRECT ANSWER: -Some agents contain substantial
amounts of sodium
-Sodium excess can exacerbate hypertension and heart failure, patients with these
disorders should avoid preparations that have high sodium content.
Antacid Patient Teaching Consitpation/Diarrhea - CORRECT ANSWER: -Some agents
can cause diarrhea or constipation
-Patients should be taught to adjust the dosage of one agent or the other to normalize
bowel function.
Antacid Uses - CORRECT ANSWER: Primary indication is treatment of PUD; Not first
line of treatment as alternate therapies may be more convenient with less AE
, Antacids MOA - CORRECT ANSWER: react with gastric acid to produce neutral salts or
salts of low acidity; by neutralizing acid, these drugs decrease destruction of the gut
wall.
Anticholinergic Drugs Contraindication - CORRECT ANSWER: patients with acute
narrow-angle glaucoma or an enlarged prostate.
Anticholinergic Drugs MOA - CORRECT ANSWER: blocks acetylcholine, preventing
bronchial constriction and narrowing of the airways, which indirectly facilitates
bronchodilation.
improve lung function by blocking muscarinic receptors in the bronchi, reducing
bronchoconstriction.
Antidiarrheal drugs fall into two major groups - CORRECT ANSWER: (1) specific
antidiarrheal drugs: Treat the underlying causative agent
(2) nonspecific antidiarrheal drugs: Treat the symptom but do not treat the agent
Antituberculosis regimens Guideline - CORRECT ANSWER: must always contain two or
more drugs to which the infecting organism is sensitive.
Aprepitant (Emend) CYP450 Enzyme Interaction - CORRECT ANSWER: Antiemetic
drug; a substrate for, inhibitor of, and inducer of CYP3A4; Warfarin Rifampin
Asthma Severity Classification Domains - CORRECT ANSWER: Impairment and Risk.
Basal insulin replacement - CORRECT ANSWER: 50% of the total daily insulin dose
which replaces insulin from fasting (overnight) and between meals.
Biguanides Drug Class - CORRECT ANSWER: Metformin
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