Exam (elaborations)
GMS6121 Exam One | Questions And Answers Latest {} A+ Graded | 100% Verified
- Course
- Institution
GMS6121 Exam One | Questions And Answers Latest {} A+ Graded | 100% Verified
[Show more]
Content preview
GMS6121 Exam One | Questions And Answers Latest {2024- 2025} A+ Graded | 100%Verified
The basic component of a virion that is required to protect the nucleic acid genome is the: - capsid
Enveloped viruses are susceptible to many environmental stresses such as dehydrating agents due to
the sensitivity of their: - lipid membrane
Each triangular face of a capsid is usually made of __ proteins. - 3
The Baltimore classification system, the most commonly used virus classification system, groups viruses
based on: - genome structure, plus reverse transcriptase
Naked capsid virus entry into a cell is usually via endocytosis, whereas enveloped viruses are released
into the cell after undergoing: - membrane fusion
The 4 things that viruses lack - (1) Enzymes that produce basic chemical building blocks
(2) Enzyme systems that generate usable energy
(3) Enzymes/tRNAs/ribosomes that direct protein synthesis
(4) Membranes that concentrate and localize key molecules
All viruses have _______ and _______, while only some viruses have ________. - nucleic acids and a
capsid; an envelope
A ________ is a complete, infectious virus particle. - virion
Naked capsids are ______ to drying, heat, detergents, and acid. - resistant
Enveloped capsids are ________ to drying, heat, detergents, and acid. - sensitive
,General stages of virus infection - 1) Adsorption
2) Entry
3) Uncoating
4) Early genes
5) Replication
6) Late genes
7) Assembly
8) Packaging
9) Release
Immunofluorescence - method that uses virus-specific antibodies to detect a specific viral protein,
usually in a tissue section biopsy or cells from fluid
ELISA (enzyme-linked immunosorbent assay) - method that uses virus-specific antibodies to detect virus
particles or secreted viral proteins in fluid
Electron microscopy - method used to detect viral particles in lesion
Cytopathic effects include: - -Cell lysis
-Rounding (or other morphological changes)
-Syncytia
-Inclusion bodies
Transformed cells display one or more of these changes: - -Loss of anchorage dependence
-Loss of contact inhibition
-Colony formation
-Immortalization
-Tumor formation in immunocompromised mice
Why do virus preps have such low infectivity? - -Not all virus particles are intact
, -Virus particles can contain defective genomes
-Virus particles can be empty
-Cells have antiviral defense mechanisms
Serology - the diagnostic detection of antibodies in serum, to measure the immune response to viral
infection
Antibodies to virus proteins are generated by _____ in response to infection. - B cells
Pathogenesis - the process by which one organism causes disease in another
The majority of viral infections are __________. - subclinical
Two components of viral disease: - -Effects of virus replication on the host
-Effects of host response on virus and the host
Tamiflu is a ________ inhibitor. - neuraminidase
An example of a live attenuated vaccine is: - polio
An example of a subunit vaccine is: - hep b
The ____________ is the most common route of viral entry. - respiratory tract
Mechanical barriers to infection in the respiratory tract include: - -Mucus traps viruses
-ciliary action propels viruses out of the lungs
-sneezing
-coughing
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller oneclass. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $13.48. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
75860 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now