What are the drug names within this class? - Amitriptyline (Elavil)
Nortriptyline (Pamelor)
Imipramine (Tofranil)
Desipramine (Norpramin)
Clomipramine (Anafranil)
Doxepin (Sinequan)
Tricyclic Antidepressants
What's the Mechanism of Action? - Inhibits the reuptake of norepinephrine and serotonin from synaptic
cleft.
Tricyclic Antidepressants
What are common side effects? - Arrhythmias
Orthostatic hypotension
Sedating
Dry mouth
Urinary retention
Tricyclic Antidepressants
What are the general clinical uses? - Refractor Depression
Fibromyalgia and other chronic pain symptoms
Tricyclic Antidepressants
What is another indication for the use of clomipramine, aside from the general clinical use? - Obsessive
Compulsive Disorder
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