Davenport University NURS126 Pharmacology in Nursing
Practice II - Exam 4 Chapters 22, 27, 28 Questions With
Complete Solutions
What are contraindications for fibric acid agents? Correct
Answers Patients with gallbladder or renal disease
-> Drug can increase risk/incidence of cholelithiasis (gallstones)
-> Drug is excreted by the kidneys
What are drug interactions associated with ACE inhibitors?
Correct Answers ↓ antihypertensive effect or predispose
patients to development of acute renal failure with NSAIDs
What are drug interactions associated with bile acid
sequestrants? Correct Answers ↓ absorption of other drugs with
concurrent use
-> Interfere with absorption of vitamins/minerals → nutritional
deficiencies from extended use
-> Take 1 hour before or 4 hours after all other drugs
What are drug interactions associated with fibric acid agents?
Correct Answers May enhance hypoglycemic effects of
antidiabetic drugs
↑ risk for bleeding with concurrent use of anticoagulants
What are nursing considerations for ACE inhibitors? Correct
Answers Assess VS
Administer initial dose at bedtime to avoid first-dose
phenomenon
,Observe for angioedema
-> Keep emergency cart & oxygen on standby
Assess for signs of infection; monitor WBC
-> Neutropenia = can't fight infection
Monitor potassium level
What are nursing considerations for alpha 2-adrenergic
agonists? Correct Answers Monitor heart rate, rhythm, &
sounds as well as ECG
-> Hold drug & notify physician if < 60
*Use same side extremity with every measurement
Assess BP lying, sitting, & standing
-> Hold drug & notify physician if < 90/60
*Use same side extremity with every measurement
Monitor blood glucose levels
-> May be ↓/↑ with beta-adrenergic blockers
Observe for S & S of hypoglycemia in diabetic patients
-> Initial signs and symptoms might not be evident with drug
use
Gradually ↑ ambulation distance & frequency
-> To determine activity tolerance
What are nursing considerations for bile acid sequestrants?
Correct Answers Obtain careful history of past GI disorders
, -> Drug can slow GI motility
Monitor for significant GI effects
Mix powder thoroughly with food or 4 - 6 ounces of fluid
What are nursing considerations for calcium channel blockers?
Correct Answers Monitor BP (lying/sitting/standing) & P;
obtain weight
Observe for S & S of HF (i.e. dyspnea, frothy pink-tinged
sputum, rales in lungs, profound fatigue, or swelling of
extremities)
-> These meds can decrease myocardial contractility, increasing
risk for heart failure
Avoid grapefruit juice
-> Reduces drug metabolism → possible toxicity
What are nursing considerations for direct-acting vasodilators?
Correct Answers IV sodium nitroprusside
-> Always dilute per manufacturer's guidelines
-> Never infuse over 10 minutes
-> Monitor VS
**Drug contains cyanide groups that are released upon its
metabolism, causing cyanide toxicity
What are nursing considerations for diuretics? Correct Answers
Monitor I/O & VS (i.e. BP & P)
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