Exam (elaborations)
CPIA Questions with complete solutions
CPIA Questions with complete solutions
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CPIA Questions with complete solutions
PHS nnPolicy nnand nnthe nnAnimal nnWelfare nnRegulations nn(AWR). nnPHS nnpolicy nnfurther nnrequires nnthat nnthe
nnprovisions nnof nnthe nnGuide nnapply nn- nncorrect nnanswer-IACUC nnreview nnof nnproposals nnthat nninvolve
nnanimals nnis nnbased nnon nncriteria nnestablished nnin nnwhat nntwo nndocuments?
Full nncommittee nnreview nnand nndesignated nnmember nnreview nn- nncorrect nnanswer-What nntwo nnmethods nnof
nnreview nnare nnrecognized nnby nnthe nnPHS nnPolicy nnand nnAWR's?
False. nnFor nna nnprotocol nnto nnbe nnapproved nnby nnthe nnfull nncommittee, nna nnmajority nnof nnthe nnquorum
nnpresent nnmust nnapprove nnthe nnprotocol. nn- nncorrect nnanswer-True nnor nnFalse: nnA nnprotocol nnreviewed nnby
nnthe nnfull nncommittee nnreview nnprocess nnmust nnreceive nnthe nnapproval nnof nnat nnleast nnthree nnpeople nnon
nnthe nncommittee.
Designated nnreview nnallows nnone nnor nnmore nnmembers nnto nnapprove nna nnprotocol. nnPrimary nnreviewers, nnin
nnthe nnfull nncommittee nnreview nnprocess, nntake nnresponsibility nnfor nnan nnin nndepth nnreview nnof nnthe
nnprotocol, nnmay nnask nnthe nnPI nnfor nnclarification, nnand nnmay nndescribe nnthe nnprotocol nnto nnthe nncommittee
nnbut nnapproval nnis nnbased nnon nna nnmajority nnvote nnby nna nnquorum nnof nnthe nnIACUC nn- nncorrect nnanswer-Use
nnof nnprimary nnreviewers nnin nnthe nnfull nncommittee nnreview nnprocess nndiffers nnfrom nndesignated nnreview nnin
nnwhat nnimportant nnway?
True nn- nncorrect nnanswer-True nnor nnFalse: nnPHS nnpolicy nnand nnAWR nnrequire nnthat nnIACUC nnmeeting
nnminutes nnreflect nncommittee nndeliberations
False: nnAn nninvestigator/IACUC nnmember nncan nnnot nncontribute nnto nna nnquorum nnthat nnis nnvoting nnon nnthe
nninvestigators nnown nnprotocol. nn- nncorrect nnanswer-True nnor nnFalse: nnAn nninvestigator nnthat nnis nnalso nnan
nnIACUC nnmember nncan nnbe nncounted nnin nna nnquorum nnof nnIACUC nncommittee nnmembers nnthat nnis nnvoting
nnon nnthe nninvestigators nnown nnprotocol.
True nn- nncorrect nnanswer-True nnor nnFalse: nnDesignated nnreview nnrequires nnthat nnall nnmembers nnof nnthe
nnIACUC nnhave nnan nnopportunity nnto nnrequest nnfull nncommittee nnreview nnof nnany nnprotocol.
, Approve, nnrequire nnmodifications nnin nnorder nnto nnapprove, nnor nnrequest nnfull nncommittee nnreview. nn-
nncorrect nnanswer-IACUC nnmembers nnassigned nnprotocols nnor nnamendments nnto nnprotocols nnfor
nndesignated nnreview, nnhave nnthe nnauthority nnto_______, nn_________ nnor nn__________.
a.) nnApproval nnof nnthe nnprotocol. nnb.) nnRequire nnmodifications nnto nnsecure nnapproval nnc.) nnWithhold
nnapproval. nnd.) nnDefer nnor nntable nnreview nnuntil nnthe nnIACUC nnhas nnall nninformation nnneeded nnto nnconduct nna
nnreview. nn- nncorrect nnanswer-After nnfull nncommittee nnreview nnof nna nnprotocol, nnwhat nnactions nnmay nnbe
nntaken nnby nnthe nnIACUC?
False: nnSignificant nnchanges nnmust nnbe nnreviewed nnand nnapproved nnbefore nnthey nnoccur nn- nncorrect
nnanswer-True nnor nnFalse: nnSignificant nnchanges nnto nna nnprotocol nnmay nnbe nnput nninto nnaction nnprior nnto
nnapproval nnby nnthe nnIACUC.
Change nnin nnobjectives; nnchange nnfrom nnnon-survival nnto nnsurvival nnsurgery; nnchange nnin nndegree nnof
nninvasiveness nnor nndiscomfort nnof nna nnprocedure; nnchange nnin nnspecies nnor nnnumber nnof nnanimals nnused;
nnchange nnin nnpersonnel nninvolved nnin nnanimal nnprocedures; nnchange nnin nnanesthetics nnor nnuse nnor nnnon-use
nnof nnanalgesics; nnchange nnin nnmethods nnof nneuthanasia; nnchange nnin nnduration, nnfrequency nnor nnnumber nnof
nnprocedures nnperformed nnon nnan nnanimal. nn- nncorrect nnanswer-Give nnexamples nnof nnwhat nnmight nnbe
nnconsidered nna nnsignificant nnchange nnto nnan nnapproved nnprotocol.
every nnthree nnyears nn- nncorrect nnanswer-How nnoften nndoes nnPHS nnpolicy nnrequire nncomplete nnIACUC nnreview
nnof nnpreviously nnapproved nnPHS nnsupported nnprotocols?
Once nna nnyear nn- nncorrect nnanswer-AWR's nnrequire nnIACUC nnreview nnof nnpreviously nnapproved nnprotocols
nnhow nnoften?
Replacement, nnReduction, nnand nnRefinement nn- nncorrect nnanswer-The nnAWR nnand nnPHS nnpolicy nnrequire
nnappropriate nnconsideration nnof nnalternatives nnto nnprocedures nnthat nncan nncause nnmore nnthan nnslight nnor
nnmomentary nnpain nnor nndistress nnin nnanimals. nnAlternatives nnare nnframed nnwithin nnthe nncontest nnof nnthe
nn3R's. nnWhat nnare nnthe nn3 nnR's?
In nnvitro nnmethods, nnuse nnof nninvertebrates nninstead nnof nnvertebrate nnanimals, nnuse nnof nnmicroorganisms
nnor nnplants, nnuse nnof nnvertebrates nnlower nnon nnthe nnphylogenetic nnscale, nnuse nnof nncomputer nnmodels, nnuse
nnof nnnonliving nnsystems nnsuch nnas nnmechanical nnmodels nnor nnchemical nntechniques. nn- nncorrect nnanswer-
Give nnexamples nnof nnreplacement.