Exam (elaborations)
BTECH Exam 2 Questions & Answers 2024/2025
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BTECH Exam 2 Questions & Answers 2024/2025
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BTECH Exam 2 Questions & Answers2024/2025
The Animal Welfare Act aims to encourage the use of animals in testing candidate human drugs -
ANSWERSWhat is not correct about the regulation of animal research under the Animal Welfare Act of
1966?
The ability of a drug to alter the sequence of DNA - ANSWERS"As part of in vitro research, the drug
candidate is tested using the Ames test for genotoxicity. Genotoxicity is a test for: "
Facilitites should be suitable for the placement of cats and mice in the same area - ANSWERSWhat is not
compliant with GLP requirements regarding facilities or operation of facilities used for animal testing?
Equipment should be using metric system measurement - ANSWERSWhat is not really a GLP requirement
regarding equipment in animal testing laboratories?
Fungus - ANSWERS"Lead compounds for drug optimization are either synthetic or derived from naturally
available compounds. In the NPR video, the chemical coumarin in sweet clover hay was converted by a
____________ to a potent chemical which caused uncontrolled internal bleeding in cows due to blood
that wouldn't clot. "
Date the testing facility manager was hired - ANSWERSWhat information is usually not included in
completed animal study reports per GLP?
The shared GLP principles are in place to impose trade barriers for tested chemicals among member
countries - ANSWERSThe OECD published a series of principles of Good Laboratory Practices and
Compliance Monitoring. What does not apply to the OECD and the GLP principles?
Education, training and experience" - ANSWERS"GLP regulations require that "each individual engaged in
the conduct, or responsible for the supervision, of a nonclinical laboratory study shall have
__________________ to enable that individual to perform the assigned functions.""
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