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NR 546 PSYCHOPHARM FINAL EXAM 2024 LATEST UPDATED COMPLETE 200 QUESTIONS WITH DETAILED VERIFIED AND 100% CORRECTANSWERS ACTUAL NEW GRADE A+ ASSURED$13.49
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NR 546 PSYCHOPHARM FINAL EXAM 2024
LATEST UPDATED COMPLETE 200
QUESTIONS WITH DETAILED VERIFIED
AND 100% CORRECTANSWERS ACTUAL
NEW GRADE A+ ASSURED
Common side effect of SSRIs - ....ANSWER...sexual
dysfunction
rapid cycling bipolar disorder - ....ANSWER...Minimum of
4 episodes a year
Goal of antidepressant therapy - ....ANSWER...complete
remission of symptoms
Serotonin GI effects - ....ANSWER...Due to the fact that
90% of 5HT receptors are located in GI tract
best tolerated SSRI - ....ANSWER...Escitalopram
(Lexapro) also has fewest CYP interactions
Lithium levels - ....ANSWER...Can be increased by
NSAIDS and ACE inhibitors
Can be decreased by caffeine and mania
1
,Unaffected by amiloride, furosemide, and sulindac
Lithium purpose - ....ANSWER...Effective treatment for
manic episodes, to prevent reoccurrence and to a lower
degree is effective in depressive episodes
Lamotrigine - ....ANSWER...Well tolerated except for the
propensity to cause a rash
Lithium - ....ANSWER...Well established to prevent
suicide in clients with mood disorders
Lithium - ....ANSWER...Has a narrow therapeutic window
and requires law draws
1st line treatment for OCD - ....ANSWER...SSRIs are first
line. Benzodiazepines are not!!!
2
,Primary action of hallucinogenic drugs such as
LSD,mescaline, psilocybin, and MDMA -
....ANSWER...Agonism of 5HT2A receptors
Hallucinogens may have additional actions at other
serotonin receptors (particularly 5HT1A and 5HT2C) and
at other neurotransmitter systems, and MDMA in
particular also blocks the serotonin transporter (SERT)
Controls appetite - ....ANSWER...hypothalamus serves as
the brain center that controls appetite by utilizing a
complex set of circuits and regulators. One formulation of
how the hypothalamus does this is the notion that there is a
major appetite stimulating pathway whose actions are
mediated by two peptides (neuropeptide Y and agouti-
related protein)
Phentermine - ....ANSWER...Acts like amphetamine,
blocking both the dopamine transporter (DAT) and the
norepinephrine transporter (NET) and, at high doses, the
vesicular monoamine transporter (VMAT)
Buprenorphine - ....ANSWER...Is also approved for <18
year olds
Disulfiram caution - ....ANSWER...Alcohol reaction may
occur within two weeks of alcohol ingestion
Methadone - ....ANSWER...Is a full mu-receptor agonist
3
, with a long half-life, which can prevent withdrawal
symptoms for 24 hours and provide steady control of
cravings throughout the day. In addition to its opioid
receptor activity, it is also an antagonist of the N-methyl-
D-aspartate (NMDA) receptor.
Hallucinogenic intoxication - ....ANSWER...pupillary
dilation, tachycardia, sweating, palpitations, blurred vision,
tremors, incoordination
Can be perceived as a panic attack and often called a bad
trip.
Can experience an acute state of confusion (delirium)
where the abuser is disoriented and agitated.
Disulfiram - ....ANSWER...Irreversibly inhibits aldehyde
dehydrogenase resulting in build of toxic levels of
acetaldehyde
Acamprosate reduces glutamate release associated with
alcohol withdrawal, naltrexone blocks the enjoyment of
heavy drinking through its action on reward circuitry.
sedative-hypnotics - ....ANSWER...Act at GABA A
receptor sites in reward circuits
Impulsive Disorders - ....ANSWER...Focused on reward
and associated with Mesolimbic pathway
4
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