NAPLEX EXAM QUESTION BANK FOR 2024-
2025 ALL QUESTIONS AND CORRECT
DETAILED ANSWERS TOP RATED
VERSION FOR 2024-2025 | A GRADED | NEW
AND REVISED
What is the difference between Continental or dry gum method and
English, or wet gum method? - ANSWER- Both have same ingredients
(oil, purified water and gum (such as acacia) in the ratio of 4:2:1 but the
order of mixing is different.
Dry method: gum is mixed rapidly with oil then water added all at once
Wet method: gum is dissolved in water first, then oil is slowly added
What you know about HLB (hydrophilic-Lipophilic balance) number? -
ANSWER- #s range from 0-20 with 10 being the mid-point means it is
the break point between water and oil solubility. #>10 means
hydrophilic (water-soluble) and #<10 means lipophilic (lipid-soluble)
What is Eutectic Mixture? - ANSWER- A eutectic mixture is two or
more components that melt at a temperature lower than the melting
temperature for the individual components.
Which of the following are common preservatives?
A. Benzalkonium chloride (BAK)
,B. Benzyl alcohol
C. Chlorhexidine
D. Thimerosal (contain mercury)
E. Sodium benzoate
F. Benzethonium chloride
G. propylparaben - ANSWER- All of them
Why preservative-free formulations if there is no harm from multi-dose
vials? - ANSWER- no scientifically conclusive evidence exists of harm
from exposure to thimerosal preservative-containing vaccine, whereas
evidence is accumulating of lack of any harm resulting from exposure to
such vaccines. Therefore, the benefits of influenza vaccination outweigh
the theoretical risk, if any, for thimerosal exposure through vaccination"
(MMWR 54 [RR08]: 1-40, 2005). Nonetheless, FDA is in discussions
with manufacturers of influenza vaccine encouraging them to further
increase the supply of preservative-free formulations.
Is it safe for pregnant women to receive an influenza vaccine that
contains thimerosal? - ANSWER- Yes. A study of influenza vaccination
examining over 2,000 pregnant women demonstrated no adverse fetal
effects associated with influenza vaccine. Case reports and limited
studies indicate that pregnancy can increase the risk for serious medical
complications of influenza. One study found that out of every 10,000
women in their third trimester of pregnancy during an average flu
season, 25 will be hospitalized for flu related complications.
Which of the following promote a better medication absorption? A.
Lotions B. Creams C. Ointments D. Pastes - ANSWER- C. Ointments
,They are not applied easily to hairy skin
Which of the following has higher potency? A. Elocon (mometasone)
ointment B. Elocon (mometasone) cream - ANSWER- A. Elocon
ointment is high potency and B is low-medium potency and reason
behind this is ointment is 80% oil
Which of the followings is 80% oil and 20% water?
A. Cream
B. Lotion
C. Ointment
D. Paste - ANSWER- C. Ointment
Cream is 50% oil and 50% water
Lotion is mostly water
Paste are the thickest ointments and are also used as protective barriers
Ex. Triple paste medicated diaper rash ointment
List the 5 classes or types of ointment bases? - ANSWER- Oleaginous
bases such as white petrolatum
Absorption bases (such as lanolin, Aquaphor)
W/O emulsion bases
O/W emulsion bases (hydrophilic ointment, Dermabase)
Water soluble or water miscible bases (PEG ointment)
, GELs - ANSWER- Gels are oil in water with alcohol base
Example: Benzoyl peroxide and erythromycin topical acne gel
(benzamycin)
Also used as Thickeners
> example of thickeners are alginates (including Na, K, Ca alginate),
agar, carrageenan, gelatin, carbomer, tergacanth, bentonite)
List some commonly used bases in suppositories preparations? -
ANSWER- cocoa butter (theobroma oil)
Glycerin
Hydrogenated vegetable oils
Polyethylene glycol (Carbowax)
What is the difference between Syrups and Elixirs? - ANSWER- Syrups
(sugar base)
Elixirs (Alcohol base)
List 2 plasticizers used to soften the capsule? - ANSWER- Glycerol and
Sorbitol
If patient can't take capsule due to Gelatin, what is the other type of
capsule that could be dispensed to these customers and it is not made
from animal? - ANSWER- Hypromellose
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