Evolution Chapter 1 Actual Real Practice Exam Questions And Answers Graded A+.
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Course
AZT
Institution
AZT
Evolution - correct answer Evolution is a change in the gene pool of a population over time.
Gene - correct answer a hereditary unit that can be passed on unaltered for many generations
gene pool - cor...
Evolution - correct answer Evolution is a change in the gene pool of a
population over time.
Gene - correct answer a hereditary unit that can be passed on unaltered for
many generations
gene pool - correct answer all of the alleles in a population in particular
generation
Biological evolution: - correct answer Specifically changes in the composition
of populations of organisms over generations
What is HIV? - correct answer - Attacks the immune system; attack the
defenses
HIV is an intracellular parasite, a type of virus called a retrovirus
HIV parasite macrophages and T-cells (important immune system compounds)
HIV replicates inside the cell and eventually kills it
- it attacks cells that will attack the virus
- specializing in our defenses
What is the HIV life cycle? - correct answer HIV virion binds and enters cell
1. HIV RNA genome
a. Same polymerase will copy the DNA
2. Copied into DNA
a. Reverse transcriptase
3. Viral DNA into human chromosome
a. Cuts the DNA of the host chromosome, inserts and seals it up with integrase
, 4. Viral gene expression
a. Mature virus is produced and released
enzymes of HIV - correct answer (1)Requires CD4 and CCR5 cell surface
proteins
(2)Requires HIV reverse transcriptase enzyme
(3)Requires the HIV integrase enzyme
(4)Requires the HIV protease to convert HIV precursor proteins to their mature forms
reverse transcriptase - correct answer -RT inhibitors: AZT, 3TC, d4T
Integrase - correct answer -Insertion of HIV DNA into human chromosome
Protease - correct answer -Processing of HIV precursor proteins into mature
forms
Fusion inhibitors - correct answer -Block cell binding and entry
AZT inhibition of reverse transcriptase - correct answer •AZT = Azidothymidine
•Looks like thymidine, but has no 3'-OH group
.•AZT can be incorporated into the DNA copy by RT, just like the natural base thymidine.
•But once AZT is in the DNA, the copy can NOT be extended any further (no 3'-OH for attachment of the
next base).
•HIV genome replication into DNA copies is stopped.
•HIV reproduction is stymied.
Why does AZT work initially? - correct answer AZT works at first, because:
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