TEST BANK For Karch Focus on Nursing Pharmacology, 9th Edition by Rebecca Tucker, Verified Chapters 1 - 59, Complete Newest Version TEST BANK For Karch's Focus on Nursing Pharmacology, 9th Edition by Rebecca Tucker, Verified Chapters 1 - 59, Complete Newest Version Test Bank For Karch’s Focus on ...
When involved in phase III drug evaluation studies, what responsibilities would the nurse
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jhave?Working with animals who are given experimental drugs
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Choosing appropriate patients to be involved in the drug study
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jMonitoring and observing patients closely for adverse effects
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jConducting research to determine effectiveness of the drug Ans: C
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Feedback:
Phase III studies involve use of a drug in a vast clinical population in which patients are asked to
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recordany symptoms they experience while taking the drugs. Nurses may be responsible for helping
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collect and analyze the information to be shared with the Food and Drug Administration (FDA) but
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would not conduct research independently because nurses do not prescribe medications. Use of animals
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in drug testing is done in the preclinical trials. Select patients who are involved in phase II studies to
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participatein studies where the participants have the disease the drug is intended to treat. These patients
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are monitored closely for drug action and adverse effects. Phase I studies involve healthy human
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volunteerswho are usually paid for their participation. Nurses may observe for adverse effects and
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toxicity.
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What concept is considered when generic drugs are substituted for brand name
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jdrugs?Bioavailability
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Critical
jconcentrationDistrib j
ution
Half-life
jAns: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is available to act
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on body cells. Binders used in a generic drug may not be the same as those used in the brand name drug.
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Therefore, the way the body breaks down and uses the drug may differ, which may eliminate a generic
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drug substitution. Critical concentration is the amount of a drug that is needed to cause a therapeutic
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effect and should not differ between generic and brand name medications. Distribution is the phase of
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pharmacokinetics, which involves the movement of a drug to the body’s tissues and is the
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, Test Bank - Focus on Nursing Pharmacology (9th Edition by Karch)
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same in generic and brand name drugs. A drug’s half-life is the time it takes for the amount of drug
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todecrease to half the peak level, which should not change when substituting a generic medication.
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A nurse is assessing the patient’s home medication use. After listening to the patient list current
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medications, the nurse asks what priority question?
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Do you take any generic medications?
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Are any of these medications orphan drugs?
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Are these medications safe to take during
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jpregnancy?Do you take any over-the-counter j j j j j
jmedications?
Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-counter medications because patients
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may not consider them important. The patient is unlikely to know the meaning of orphan drugsunless
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they too are health care providers. Safety during pregnancy, use of a generic medication, or classification
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of orphan drugs are things the patient would be unable to answer but could be found in reference books if
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the nurse wishes to research them.
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After completing a course on pharmacology for nurses, what will the nurse
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jknow?Everything necessary for safe and effective medication administration
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Current pharmacologic therapy; the nurse will not require ongoing education for 5 years.
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jGeneral drug information; the nurse can consult a drug guide for specific drug
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jinformation.The drug actions that are associated with each classification of medication Ans:
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C
Feedback:
After completing a pharmacology course nurses will have general drug information needed for safe
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andeffective medication administration but will need to consult a drug guide for specific drug
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information before administering any medication. Pharmacology is constantly changing, with new drugs
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entering the market and new uses for existing drugs identified. Continuing education in pharmacology is
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essential to safe practice. Nurses tend to become familiar with the medications they administer most
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often, but there will always be a need to research new drugs and also those the nurse is not familiar
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withbecause no nurse knows all medications.
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