HMX Practice Pharmacology Quiz 2024.
HMX Practice Pharmacology Quiz 2024.
HMX Practice Pharmacology Quiz 2024.
HMX Practice Pharmacology Quiz 2024.
HMX Practice Pharmacology Quiz 2024.
HMX Practice Pharmacology Quiz 2024.
Toxicity cause by binding of drug to its intended receptor in unintended tissue is an
example of ____ drug toxicity? ==on target
The classical small molecule drugs and the newer therapeutics, such as biologics, differ
in many ways. The defining difference between these drug modalities is their
==molecular weight
A monoclonal antibody is an example of a ==protein-based therapy
The ____________ index of a drug indicates the margin of safety of the drug.
==therapeutic
If the elimination rate of a drug does not increase when the concentration of the drug in
the plasma increases, this drug most likely follows ____________. ==zero-order
kinetics
Calculating the therapeutic dose of a drug involves a determination of the
____________ of the drug ==ED50
The goals of ____________ clinical trials are to determine the efficacy and tolerability of
an investigational drug, often in comparison to a standard of care medication for the
condition of interest. ==phase III
When determining the bioavailability of a drug administered by a given route, if a
____________ fraction of drug reaches the ____________, then the bioavailability,
expressed as a percentage, will be low.
Which of the following types of drugs will decrease the basal activity of a receptor?
==inverse agonist
A drug discovery approach that uses an endogenous ligand as the starting point for
development is considered to be ____________-centered drug discovery.
==compound
Which of the following is most likely the primary renal process by which a polar,
hydrophobic drug with a low affinity for plasma proteins moves from the plasma into the
urine? ==filtration
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