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WGU D027 OA EXAM LATEST 3 VERSIONS AND STUDY GUIDES ALL 600
QUESTIONS AND DETAILED SOLUTIONS WITH EXPLANATIONS LATEST
2024-2025 UPDATE
WGU D027 OBJECTIVE ASSESMENT EXAM 1
QUESTION: A patient has endured several dosage adjustments of his tricyclic antidepressant, so
the provider recommends genetic testing. Which statement correctly describes the rationale
for genetic testing?
a. The CYP2D6 gene influences metabolism of tricyclic antidepressants and certain other drugs.
b. The HER2 gene is a tumor marker that impacts metabolism of tricyclic antidepressants.
c. The BRCA2 gene influences metabolism of certain drugs and increases the risk for breast
cancer.
d. The x linked OPN1MW gene for male color blindness also slows metabolism of certain -
ANSWER-a. The CYP2D6 gene influences metabolism of tricyclic antidepressants and certain
other drugs.
HER2 is a gene often implicated with cancer, as is BRCA2. OPN1MW is the gene that codes for
color blindness in men. Metabolism of 25% of all prescribed drugs, including tricyclic
antidepressants, beta adrenergic receptor blockers, and neuroleptics, is influenced by variants
in a certain gene, requiring genetic testing to reduce trial-and-error in estimating appropriate
drug-dosage levels.
QUESTION: According to the Centers for Disease Control and Prevention, the 10 most costly
chronic conditions include cardiovascular diseases, obesity, asthma, diabetes, smoking and
alcohol related conditions, cancer, Alzheimer's disease, arthritis and stroke. Which are the top 4
in ranking from most costly to least costly?
a. Cardiovascular diseases, obesity, diabetes, cancer
b. Cardiovascular diseases, diabetes, obesity, cancer
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c. Cardiovascular diseases, Smoking-related conditions, Alcohol-related conditions, diabetes
d. Cardiovascular diseases, Stroke, Obesity, Diabetes - ANSWER-c. Cardiovascular diseases,
Smoking-related conditions, Alcohol-related conditions, diabetes
QUESTION: A mother brought her child to the doctor for genetic testing. The health care
provider was trying to explain the genetic results of the child. During his explanation he tells the
mother that the child has 2 X chromosomes and a Y chromosome in each cell. He begins to
explain some physical appearances the mother might notice on her son. He explains that she
might notice that he has sparse body hair, long limbs and small testes. The health care
practitioner is explaining which syndrome to the mother.
a. Klinefelter syndrome
b. Turners' syndrome
c. Down syndrome
d. Kawasaki's disease - ANSWER-a. Klinefelter syndrome
Klinefelter syndrome is an individual with at least 2 X chromosomes and a Y chromosome in
each cell. Because of the Y chromosome these individuals have a male appearance, but they are
usually sterile and about half develop female-like breasts.
QUESTION: A patient reports a maternal family history of Lynch syndrome. Which laboratory
finding might indicate a need for further testing for the presence of Lynch syndrome in this
patient?
a. Elevated thyroid-stimulating hormone
b. Low cortisol level
c. Positive heme-occult test
d. Sputum positive for Pseudomonas Aeruginosa - ANSWER-a. Positive heme-occult test
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Positive heme-occult because Lynch syndrome is a hereditary form of colorectal cancer and
colorectal bleeding can be a sign of cancer
QUESTION: An individual's acquired immunity is dependent on the function of which cells?
(Select all that apply.)
a. B lymphocytes
b. Opsonins
c. T lymphocytes
d. Macrophages - ANSWER-a. B lymphocytes
c. T lymphocytes
d. Macrophages
T lymphocytes, B lymphocytes, macrophages, and dendritic cells are involved in acquired
immunity.
QUESTION: A 17-year-old female comes to the clinic for a physical exam. As part of the visit, the
APRN considers her risk factors for type 2 diabetes mellitus (T2DM). Risk factors for T2DM
would likely include all of the following except:
a. Native American ancestry
b. Family history of type 1 diabetes mellitus (T1DM)
c. Obesity
d. Personal history of polycystic ovary syndrome (PCOS) - ANSWER-b. Family history of type 1
diabetes mellitus (T1DM)
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Type 1 diabetes has the genetic link and is something they are born with
QUESTION: Some older adults have impaired inflammation and wound healing because of
which problem?
a. Circulatory system cannot adequately perfuse tissues.
b. Complement and chemotaxis are deficient.
c. Underlying chronic illness(es) exists.
d. Number of mast cells is insufficient. - ANSWER-c. Underlying chronic illness(es) exists.
QUESTION: A patient is diagnosed with chronic obstructive pulmonary disease (COPD) and has
elevated pulmonary vascular resistance. Which symptom would indicate the need to assess for
the complication of cor pulmonale (right-sided heart failure)?
a. crackles bilaterally
b. generalized arthralgia
c. jugular venous distention
d. occasional constipation - ANSWER-c. jugular venous distention
Symptoms of right-sided heart failure include the following: hepatosplenomegaly, extremity
edema, ascites, jugular venous distention
QUESTION: A parent asks the healthcare professional to explain why a child diagnosed with
Tetralogy of Fallot squats often. What explanation by the professional is best?
a. It helps to alleviate chest pain
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