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Exam (elaborations)

Depressants Practice Exam Questions And Correct Verified Answers.

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  • Course
  • NA 701
  • Institution
  • NA 701

How do CNS depressants act? - correct answer Decrease overall neuronal function CNS depressants medical treatment of what? - correct answer Benzodiazepines & barbiturates treat anxiety, insomnia, convulsi...

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  • August 20, 2024
  • 6
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers
  • NA 701
  • NA 701
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RealGrades
Depressants

How do CNS depressants act? - correct answer Decrease overall neuronal
function



CNS depressants medical treatment of what? - correct answer
Benzodiazepines & barbiturates treat anxiety, insomnia, convulsions, muscle spasms



What are benzodiazepines & barbiturates abused for? - correct answer
Euphoric, sedative, & anxiolytic effects (decreased anxiety)



Ethanol has effects on what? - correct answer CNS, cardiovascular system, &
kidneys



Alcoholism has adverse effects on what? - correct answer CNS, liver,
cardiovascular system, gastrointestinal tract, hormone levels



What do CNS depressants do? (Mechanism of Action) - correct answer Elevate
inhibitory neurotransmitter activity (GABA) and suppress excitatory neurotransmitter activity
(glutamate)

-MOA: suppress ("depress") neuronal function by enhancing GABA receptor activity, which causes CNS
depression



3 categories of CNS depressants - correct answer Benzodiazepines,
benzodiazepine-like drugs, & barbiturates



Adverse effects of CNS depressants - correct answer suppression of respiration
& heart rate/blood pressure



Benzodiazepine Drugs - correct answer Diazepam (Valium) & Alprazolam
(Xanax)

, Benzodiazepine Therapeutic Uses - correct answer 1. Anti-Anxiety: (relief of
anxiety & stress). Treatment of stress & general anxiety disorder (GAD)

2. Sedative = relaxant/Hypnotic = induces sleep: (sleep aid)

3. Anticonvulsant: treatment of epilepsy

4. Muscle Relaxant: treatment of spasm & tension



Flumazenil (Romazicon) - correct answer Benzodiazepine Antagonist.
Competes with benzodiazepines for receptor binding. Treat drowsiness associated with
benzodiazepines. Treat drug overdose. Used following surgery if sedative given. Help restore normal
GABA signaling



Benzodiazepine-like Therapeutic Uses - correct answer 1. Induce Sleep: Act on
GABA. Effective sleep induction not maintenance

2. Anti-convulsant/muscle relaxant @ 10-20x dose for sedation



Benzodiazepine-like Drugs - correct answer ('z-drugs')

Zolpidem (Ambien), Zaleploon (Sonata), & Eszopiclone (Lunesta)



Date Rape Drugs - correct answer -Fluitrazepam (Rohypnol aka 'roofies')

*Sleeping Pill

-GHB - gamma hydroxybutyric acid

*Odorless, liquid non-benzodiazepine, prevents memory storage, originally general anesthetic.

*AKA: liquid ecstasy, grievous bodily harm, date rape drug



Barbiturates - correct answer Previously used as sedative/hypnotics. Long
acting anticonvulsant (treatment of seizures)



Barbiturate Drugs - correct answer Phenobarbital (Luminal)

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