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PHPR860D Vascular Access Infections-Edocarditis Study Set Exam
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PHPR860D Vascular AccessInfections-Edocarditis Study Set Exam
Treatment for UNCOMPLICATED (fever and bloodstream infection resolve w/in 72
hours) staphylococcus aureus infection associated with SHORT-TERM CVC or AC
placement - Answer remove catheter
MRSA: vancomycin, linezolid, daptomycin
MSSA: nafcillin, oxacillin, cefazolin
at least 14 days as long patient does not have immunosuppression, cancer, diabetes,
endocarditis, suppurative thrombophilia, or an additional intravascular device
(catheter)
if patient has any of the above, treatment is for 4-6 weeks
Treatment for UNCOMPLICATED (fever and bloodstream infection resolve w/in 72
hours) coagulase negative staphylococcus aureus infection associated with
SHORT-TERM CVC or AC placement - Answer remove cathater
use vancomycin, linezolid, or daptomycin
tx for 5-7 days
*note: coagulase negative staph (s. epididermis) is often methicillin-resistant so
nafcillin, oxacillin, cefazolin would not be appropriate (they are methicillin
susceptible/treat MSSA)
Treatment for UNCOMPLICATED (fever and bloodstream infection resolve w/in 72
hours) enterococcus infection associated with SHORT-TERM CVC or AC placement -
Answer remove catheter
ampicillin or penicillin or vancomycin
if VRE: either daptomycin or linezolid
tx for 7-14 days
Treatment for UNCOMPLICATED (fever and bloodstream infection resolve w/in 72
hours) gram-negative infection associated with SHORT-TERM CVC or AC placement -
Answer remove catheter
tx for 7-14 days
Treatment for UNCOMPLICATED (fever and bloodstream infection resolve w/in 72
hours) candida infection associated with SHORT-TERM CVC or AC placement - Answer
tx echinocandin and de-escalate to azole therapy
, tx for 14 days after last negative blood culture (as long as eye exam confirms no fungal
growth; if fungal growth in eye is present, tx for 28 days)
Treatment for COMPLICATED infections including suppurative thromobophilia,
endocarditis, and osteomyelitis associated with SHORT-TERM CVC or AC placement -
Answer complicated infections, suppurative thrombophilia and endocarditis: 4-6 weeks
osteomyelitis: 6-8 weeks
remember: if pt is immunosuppressed, has diabetes, cancer, or an additional catheter,
and has a vascular access infection w/ staph aureus, they need to be on therapy for 4-6
weeks
Treatment for UNCOMPLICATED (fever and bloodstream infection resolve w/in 72
hours) staphylococcus aureus infection associated with LONG-TERM CVC or port
placement - Answer remove catheter
tx w/ same drugs
tx for 4-6 weeks
Treatment for UNCOMPLICATED (fever and bloodstream infection resolve w/in 72
hours) coagulase negative staphylococcus aureus infection associated with
LONG-TERM CVC or port placement - Answer may retain CVC/P
tx w/ same drugs
tx for 10-14 days + antibiotic lock therapy for 10-14 days
*if persisting/relapsing bacteremia, remove CVC/P and identify if complicated is present
& treat accordingly
Treatment for UNCOMPLICATED (fever and bloodstream infection resolve w/in 72
hours) enterococcus infection associated with LONG-TERM CVC or port placement -
Answer may retain CVC/P
tx w/ same drugs
tx for 7-14 days w/ systemic abx + antibiotic lock therapy for 7-14 days
*if persisting/relapsing bacteremia, remove CVC/P and identify if complicated is present
& treat accordingly
Treatment for UNCOMPLICATED (fever and bloodstream infection resolve w/in 72
hours) gram-negative infection associated with LONG-TERM CVC or port placement -
Answer can remove CVC/P
if choosing to salvage CVC/P, tx for 10-14 days w/ systemic abx + 10-14 days of antibiotic
lock therapy
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