SBB Review Exam Questions and
Answers Latest Verified
Sensitivity formula - CORRECT ANSWER-TP/(TP+FN) sensitivity looks at true positives
specificity formula - CORRECT ANSWER-TN/(TN+FP) specificity looks at true
negatives
Positive predicted value formula - CORRECT ANSWER-TP/(TP+FP)
Negative predictive value formula - CORRECT ANSWER-TN/(TN+FN)
What is the half life of FVIII? - CORRECT ANSWER-8-12 hours
What is the half life of IgG? - CORRECT ANSWER-23-25 days
At what rate does the hematocrit of stores RBCs decrease? - CORRECT ANSWER-1%
per day
What is the impact of one RBC transfusion? - CORRECT ANSWER-Hgb up 1 g/dL and
Hct up by 3%
What is the impact of one plasma unit transfusion? - CORRECT ANSWER-Increases
stable coag factors by 10%
What is the impact of a whole blood derived platelet? - CORRECT ANSWER-5-10k
increase
What is the impact of an apheresis platelet? - CORRECT ANSWER-50-60k
What is the FVIII dose assumed per bag if cryo? - CORRECT ANSWER-80 IU FVIII
What is the fibrinogen dose per bag of cryo? - CORRECT ANSWER-150 mg
What is the formula for fetal maternal hemorrhage? - CORRECT ANSWER-(Fetal cells /
total cells counted) X maternal blood volume
What is the assumed maternal blood volume? - CORRECT ANSWER-5000 mL
What is the acceptable corrected count increment minimum? - CORRECT ANSWER-
7500
, What is the CCI formula? - CORRECT ANSWER-((Post platelet count - pre platelet
count) X body surface area) / number of plt transfused
What is the maximum volume you can draw from a blood donor? - CORRECT
ANSWER-10.5 mL/kg
What is the maximum extracorporeal volume for apheresis? - CORRECT ANSWER-
15% of total blood volume
What is the zone of equivalence? - CORRECT ANSWER-The concentration of antigen
and antibody
How does LISS work? - CORRECT ANSWER-Increases rate of antibody uptake
How does PEG work? - CORRECT ANSWER-Removes H2O to concentrate the
antibody
How do papain and ficin work? - CORRECT ANSWER-Reduced the zeta potential by
removing negative charge from the RBC membrane
How does BSA work? - CORRECT ANSWER-Reduces the repulsion between cells
What lectin is anti-A1 - CORRECT ANSWER-Dolichos biflorus
What lectin is anti-H - CORRECT ANSWER-Ulex europaeus
What lectin is Anti-N - CORRECT ANSWER-Vicia graminea
What lectin is anti-M - CORRECT ANSWER-Iberia amara
What can cause polyagglutination? - CORRECT ANSWER-Bacteria cleaving
carbohydrates and abnormal synthesis of the RBC membrane
What is the A3 phenotype known to cause? - CORRECT ANSWER-Mixed field
reactions
Which weak D types are treated as Rh positive? - CORRECT ANSWER-1, 2, 3, 4, and
4.1
What are the components of a quality management system? - CORRECT ANSWER-
Organizational structure, responsibilities, policies, processes, procedures, and
resources needed
Why would something be reported to the FDA during blood collection? - CORRECT
ANSWER-If there was a deviation, such as improperly cleaning an arm
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