100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Previously searched by you
Previously searched by you
logo
FNP II Question and answers rated A+ $12.99   Add to cart
Quickly navigate to
Preview
  2.  
  3. Musculoskeletal
  4.  
  5. Musculoskeletal

Exam (elaborations)

FNP II Question and answers rated A+
 9 views  0 purchase
  • Course
  • Musculoskeletal
  • Institution
  • Musculoskeletal

FNP II Question and answers rated A+ FNP II - MSK What is rheumatoid arthritis? Describe the overview, etiology, and pathophysiology - correct answer · Overview o Systemic, multisystem inflammatory disorder o Affects synovial membrane of joints o Periods of exacerbation & remission o Immu...

[Show more]

Preview 4 out of 38  pages

Document information

  • August 18, 2024
  • 38
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • fnp ii
  • fnp ii question and answers rated a

Written for

  • Musculoskeletal
  • Musculoskeletal

Seller

avatar-seller
Academia199

Reviews received

Content preview

FNP II - MSK
What is rheumatoid arthritis? Describe the overview, etiology, and
pathophysiology - correct answer ✔· Overview
o Systemic, multisystem inflammatory disorder
o Affects synovial membrane of joints
o Periods of exacerbation & remission
o Immune response in genetically




· Etiology
o Theories:
§ Autoimmune
§ Infectious trigger
o Genetics
§ Family hx of RA
o Stress
§ Exacerbation of sx sometimes prescribe antidepressants to reduce


· Pathophysiology
o Rheumatoid factor develops in synovium
o Antibody/antigen complexes --> inflammation in joints
o Synovitis develops
o Hypertrophied synovium (lining) thickens & invades surrounding tissue
o Granulation formus (pannus)
§ Pannus

,· Erodes & destroys articular cartilage
· Affects tendons & ligaments
§ Laxity, subluxation & contracture
§ Nodules, ankylosing joints


Describe the presentation and clinical sx of rheumatoid arthritis - correct
answer ✔· Presentation
o Uniform joint space narrowing
o Marginal erosion of bare areas where synovium lies on bone
o Joint subluxation
o Muscle atrophy
o Inflammation of tendon
o Extra-articular manifestations


· Clinical sx
o Pain, swelling in hands & feet
o Morning stiffness, stiffness after rest
o Less of ROM
o Generalized fatigue
§ Severe during flare up
o Rheumatoid nodules
o Flares & remissions


Describe the tx for rheumatoid arthritis - correct answer ✔o Drug therapy
pyramid
§ NSAIDs
§ Biologic response modifiers (BRMs)

,· Non-TNF-abatacept, rituximab, tocilizumab
· Anti-TNF- adalimumab, etanercept, infliximab, certolizumab pegol,
golimumab
§ Steroids
§ Disease modifying anti-rheumatics (DMARDs)
· Hydroxychloroquine, leflunomide, MTX, minocycline, sulfasalazine
· Therapeutic effect may take weeks
o PT/OT
§ ROM exercises
§ Strength/endurance exercises
§ Splints
§ Fxnl abilities
o Therapeutic use of heat/cold
o Surgery - joint replacement


What are the complications of RA? - correct answer ✔o Flexion contractures
o Joint instability
o Tendon rupture
o Septic arthritis
o Cord compression
o Sensory/motor loss


Given an overview and epidemiology of Sjogren's syndrome - correct answer
✔· Chronic inflammatory autoimmune disorder r/t exocrine dysfxn
· Dryness of lacrimal, salivary glands
· May also affect skin, lungs, kidneys, heart
· Possibly affects hematopoietic system --> lymphoma

, · Epidemiology
o 4:100,000 ppl worldwide affected
o Primary or secondary
o Affects women 9x more often than men
o Age 40-60 yrs
o Typically accompanies underlying rheumatic diseases (RA, SLE, systemic
sclerosis)


Describe the pathophysiology of Sjrogen's syndrome - correct answer ✔o
Lymphocytic infiltration in all affected organs is hallmark of SS
o Pooling of lymphocytes, plasma cells in lacrimal & parotid glands
o Characteristics "dry eye" conjunctivitis (keratoconjunctivitis sicca)
o Parotid enlargement, diminished salivary excretions
o Hyperplasia of ductal epithelium in salivary glands produces characteristics
dry mouth ("xerostomia")
§ T-lymphocytes (CD4 + T-helper subset) w/TCRab receptors
§ Genetic predisposition
§ Importance of autoantibodies (Acetylcholine receptors) in salivary glands
may impair secretion of saliva
o Infection by viruses:
§ EBV
§ Retroviruses (human T-cell lymphatic virus)
§ HepC
§ Coxsackievirus
§ Disorders of estrogen: postmenopausal and estrogen tx (circumstantial
evidence)

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller Academia199. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $12.99. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

67866 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$12.99
  • (0)
  Add to cart