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Bio 436 Lecture 7 Cardiac Cells Test Questions and Correct Answers $8.99   Add to cart

Exam (elaborations)

Bio 436 Lecture 7 Cardiac Cells Test Questions and Correct Answers

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  • BIO 436
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  • BIO 436

Sarcomere The basic unit of muscle contraction. A unit of proteins between Z-discs Thin Filaments (actin, tropomyosin, troponin) Thick Filaments (myosin) Stabilizer proteins (titin, nebula) Sequential events of contraction Ca+ binds to troponin> moves tropomyosin exposing actin> 1. Cross b...

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  • August 18, 2024
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  • BIO 436
  • BIO 436
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Bio 436 Lecture 7 Cardiac Cells Test
Questions and Correct Answers
Sarcomere ✅The basic unit of muscle contraction.

A unit of proteins between Z-discs

Thin Filaments (actin, tropomyosin, troponin)
Thick Filaments (myosin)
Stabilizer proteins (titin, nebula)

Sequential events of contraction ✅Ca+ binds to troponin> moves tropomyosin
exposing actin>
1. Cross bridging myosin to actin
2. Power stroke ADP & P released
3. Detachment binding of ATP
4. Cocking of myosin head ATP split into ADP & P

Cardiac and Skeletal Muscle Similarities ✅Microscopically similar to skeletal muscle in
many ways:
- Basic contractile unit is the sarcomere

Cardiac and Skeletal Muscle Differences ✅-cardiac fibers (cells) don't stretch length or
width of the heart (more individual and normal sized cell)

-at the end of cells, they have the Intercalated discs with the desmosomes, gap
junctions

-cardiac muscle has very little SR

-majority of Ca++ for crossbridging comes from outside of the cell

-Cardiac muscles fibers cannot undergo tetanus due to long refractory period

Intercalated discs ✅Cardiac fibers form these where they meet, in which the cell
membranes interdigitate extensively

Desmosomes ✅form tight connections so that cardiac cells don't pull apart during
contractions.

-proteins inside the cell that form as an anchor

"velcro"

, Gap junctions ✅provide channels for electrical continuity and propogation throughout
the heart

made up of proteins called connexions?
-All ions can pass through Na+, K+, Ca+

Syncitium ✅Cells that are linked together via gap junctions

with many respects they act like one large cell.

one of the atria and another on the ventricles

Myogenic ✅Because of the autorhythmic cells which are linked to the contracting cells
through gap junctions, the atrial and ventricular cells are referred to as __________?

SA node ✅pacemaker cells

located in the right atrium

dictates heartbeat

show the fastest rate of spontaneous depolarization

1% of total cells

Action potentential of Pacemaker cell ✅No sarcomeres in pacemaker cells

Pacemaker potential (HCN) - Na+ Slow depolarization > Threshold

VGCa2+C > Up Stroke (Depolarization)

VGK+C > Repolarization

HCN (hyperpolarized- activated cyclic-nucleotide channels) ✅contained in all
pacemaker cells (leaky channels)

Spontaneous depolarization is caused by Na+ flowing through channel that opens when
hyper polarized

cannot stop polarizing

Sinus venosus ✅frog's SA node

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