BMS 430 Exam 3 Questions With
Correct Answers
What is different about birds genetic sex? - answerXX is male
XY is female
What is different about the genetic sex of fish? - answerCan be either (XX or XY) depending
on species
Sometimes determined by temperature
Some have the ability to switch
...
BRIGHTSTARS EXAM STUDY SOLUTIONS 8/15/2024 2:05 PM
BMS 430 Exam 3 Questions With
Correct Answers
What is different about birds genetic sex? - answer✔✔XX is male
XY is female
What is different about the genetic sex of fish? - answer✔✔Can be either (XX or XY) depending
on species
Sometimes determined by temperature
Some have the ability to switch
What gene does the Y chromosome carry which is important in sex differentiation? -
answer✔✔SRY gene
Testosterone---->DHT by - answer✔✔enzyme 5 alpha reductase
Testosterone---->estradiol by - answer✔✔aromatase enzyme
PDG - answer✔✔are stem cells in the gonads
What is the SRY gene? - answer✔✔Sex Reversal Y gene
AKA as TDF (testis determining factor)
How does the SRY gene differentiate gonads? - answer✔✔Turns on Sox 9, a box set of genes
which influences sertoli and leydig cells to differentiate the gonads into testis
What do the Sertoli cells produce under the influence of the SRY gene? - answer✔✔MIF -
mullarian-inhibiting factor
Causes the mullerian duct regression
What do the Leydig cells produce under the influence of the SRY gene? -
answer✔✔Testosterone
- development of Wolffian ducts
(Vas deferens, seminal vesicles, epidymis)
, BRIGHTSTARS EXAM STUDY SOLUTIONS 8/15/2024 2:05 PM
- DHT >> penis and scrotum development
What duct is preprogrammed to develop? - answer✔✔Mullerian
What hormone masculinizes the brain? - answer✔✔estradiol
What protein in females prevents estradiol from crossing the BBB and masculinizing the brain? -
answer✔✔alpha fetoprotein produced by the liver binds and degrades estradiol
Why can male brains be masculinized? - answer✔✔Testosterone isn't bound by alpha fetoprotein
so it crosses the BBB, attaches to receptors and is converted into estradiol
Once masculinized, the male brain converts into what three parts? - answer✔✔Pulse generator
Aggression center
Libido center
Describe the pulse generator - answer✔✔- releases GnRH in pulses 90 min
- negative feedback from:
progesterone
estradiol
testosterone
DHT
Describe the aggression center - answer✔✔estradiol causes the production of testosterone
receptors
testosterone can trigger aggression
Libido center - answer✔✔Maintained with estradiol receptors
T--->Estradiol induces male libido effects
De la Chapelle disorder - answer✔✔XX
SRY translocation onto X chromsome
Tract: male
Phenotype: male
Brain: male
under developed--->doesn't act like man
Swyer Disorder - answer✔✔XY
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