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Pathophysiology SLCC Guaranteed Solutions

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Pathophysiology SLCC Guaranteed Solutions Homeostasis - Definition: - The body's ability to maintain a dynamic steady state of internal balance or equilibrium. Cell Changes 1. Hyperplasia - Definition: Increased number of cells. 2. Hypertrophy - Definition: Increased size of cells. - Ca...

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  • August 16, 2024
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Pathophysiology SLCC Guaranteed Solutions


Homeostasis

- Definition:

- ✅ The body's ability to maintain a dynamic steady state of internal balance or equilibrium.



Cell Changes

1. Hyperplasia

- ✅ Definition: Increased number of cells.



2. Hypertrophy

- ✅ Definition: Increased size of cells.

- Causes: Increased workload or pathological conditions.



3. Atrophy

- ✅ Definition: Reduced size of cells.

- Causes: Disuse, malnutrition, and decreased blood flow.



4. Metaplasia

- ✅ Definition: Replacement of one cell type with another that can better endure stress.

- Causes: Chronic inflammation or irritation.



5. Dysplasia

- ✅ Definition: Abnormal cell growth of a specific tissue.

- Preceding Condition: Indicates potential cancerous changes.



Cellular Changes Related to Sodium and Calcium

- Sodium Build-up:

, - ✅ Occurs due to the breakdown of the sodium-potassium pump.

- Consequence: Sodium collects in the cell, attracting water and causing intracellular swelling.



- Fatty Changes:

- ✅ Lipid accumulation in cells leads to impaired cell functions, often resulting in conditions like "fatty
liver."



- Calcium Build-up:

- ✅ Calcium accumulates due to the breakdown of the Ca²⁺/Mg²⁺ pump.

- Consequence: Inappropriate activation of cellular enzymes.



Cell Death Mechanisms

1. Apoptosis

- ✅ Controlled cell death (implosion) where all components remain within the cell, eliciting no
inflammatory response.



2. Necrosis

- ✅ Uncontrolled cell death (explosion) where cell contents are released into the extracellular space,
triggering an inflammatory response.



Organs of the Immune System

- Bone Marrow: Produces RBCs, WBCs, and platelets.

- Thymus Gland: Site of T-cell production.

- Lymph Nodes

- Tonsils

- Spleen



Telomeres

- ✅ Outermost tails of the chromosome arms.

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