Exam (elaborations)
Case Study - Novel Coronavirus Disease (COVID- 19) Part I: Emergency Department (ED) SKINNY
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Case Study - Novel Coronavirus Disease (COVID- 19) Part I: Emergency Department (ED) SKINNY
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Case Study - NovelCoronavirus Disease (COVID-
19) Part I: Emergency
Department (ED) SKINNY
,
, +ssRNA - ✔✔ANSW✔✔..Genome of COVID-19
1. +ssRNA, is
2. Largest
3. IV - ✔✔ANSW✔✔..Coronavirus:
1. ___, it (is/is not) enveloped, and it's genome size is 26-32kb.
2. (Smallest/Largest) +ssRNA virus
3. Coronavirus is a Class ___ virus
1. 229E
2. NL63
3. OC43
4. HKU1 - ✔✔ANSW✔✔..7 Coronavirus serotypes have been associated with disease
in humans:
1. HCoV-___ (alpha coronavirus)
2. HCoV-___ (alpha coronavirus)
3. HCoV-___ (beta coronavirus)
4. HCoV-___ (beta coronavirus)
5. MERS-CoV (the beta coronavirus that causes MERS)
6. SARS-CoV (the beta coronavirus that causes SARS)
7. SARS-CoV-2 (COVID-19)
1. Fever
2. Cough
3. trouble breathing - ✔✔ANSW✔✔..Coronavirus symptoms are a
1. __ of 100F or higher
2. ___
3. ___ __
1. positive, polyprotein, non-structural
2. 4
a) Spike (S), membrane (M), envelope (E), and nucleocapsid (N) -
✔✔ANSW✔✔..Genome of Coronaviruses
1. The first two-thirds of the 26-32 Kb, ___ sense RNA genome encodes a large __
(ORF1a/b) that's proteolytically cleaved to generate 15 or 16 __-___ proteins (nsps;
nsps for severe acute respiratory syndrome coronavirus)
2. The 3'-end third of the genome encodes four structural set of accessory proteins:
a) Spike (S), membrane (M), envelope (E), and nucleocapsid (N)
b) Along with a set of accessory proteins that are unique to each virus species
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