LAT Laboratory Animal Technician
Questions and Answers
U.S. Government provides approximately how much in research/development funds
spent by college and university?
✓ ~~~2/3
What information is important on grant applications to request funds?
✓ ~~~Detailed description of research goals, scientific basis of study, and review of relevant
literature and all procedures to be performed
What is the difference between NIH & NSF?
✓ ~~~NIH: primary granting agency: academia, federal agencies, biomedical research
NSF: Basic research in math, medicine, and biology
The USDA stands for what?
✓ ~~~United States Department of Agriculture
The USDA is responsible for what?
✓ ~~~Enforces and amends AWA
Auction, sale, exhibit, transport, breeding, or conduct of research with animals
Animals exempt from AWA
Research institutions mst register with
Supply annual reports
Inspection records through the FOIA
,Unscheduled inspection once per year
What does the FOIA stand for?
✓ ~~~Freedom of Information Act - provides the USDA's inspection records
What is the Public Health Service Policy?
✓ ~~~Institutions which receive funding from PHS and NIH must follow these guidelines,
requires filing of an Amimal Welfare Assurance document that demonstrates the
institution is following the Guid, PHS policy, AWA, and any other applicable laws
The FDA has many responsibilites including:
✓ ~~~Assures that new drugs and medical devices are safe and effective before approved
for use in humans
Monitors drug approval
Includes human, and veterinary drugs, food, and medical devices
Requires that effectiveness be demonstrated through well controlled investigations
What is GLP?
✓ ~~~Good Laboratory Practices
Established in 1978 with implementation of laboratory audits and inspection
programs
Details requirements for QA and SOPs
What is the importance of importation and transportations regulations?
, ✓ ~~~For the protection of humans and environment from potential disease carrying
organisms
Which agencies control importation?
✓ ~~~CDC, USDA, and US Fish & Wildlife Service
Institutional polices are established for:
✓ ~~~facility operations
care and use procedures
veterinary support
physical plant
Standard operating procedures relate to:
✓ ~~~wall aspects of animal care and support
personnel management
health surveillance of animals and personnel
equipment
investigators
What are the functions of IACUCs and who mandates?
✓ ~~~mandated by AWA, PHS policy, and the Guide
Review and approve protocols for animal use
Review animal use program and perform animal facilities inspections at least every 6
months
, What has to happen before animal research can begin?
✓ ~~~principal investigator provides written details of how animals will be used in the
research project
IACUC must review all protocols using animals and must approve all protocols
before any animal research can begin
What does the IACUC determine?
✓ ~~~Can deny permission ro start a project
can stop a research peoject
Ensures compliance with regulations
Reviews complete protocols at least every 3 years; reviews updates to protocols
yearly
What is the AAALAC, International?
✓ ~~~Association for Assessment and Accreditation of Laboratory Animal Care,
International
Non-profit organization that provides a mechanism for peer review of animal care
and use programs by scientific community
Detailed application with information on facilities, procedures, programs, and
research animals to use
Annual report must be submitted to AAALAC on status of animal care program
Site inspection and program evaluation every 3 years
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