Exam (elaborations)
6 Drugs for Tuberculosis, Fungal, and Parasitic Infections
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- Minnesota State University, Mankato
6 Drugs for Tuberculosis, Fungal, and Parasitic Infections
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Chapter 06: Drugs for Tuberculosis, Fungal, and Parasitic InfectionsMULTIPLE CHOICE
1. A patient newly diagnosed with tuberculosis (TB) asks how this infection is transmitted.
What is your best response?
a. “TB can be transmitted by ingesting contaminated foods.”
b. “TB is transmitted by living in unsanitary conditions.”
c. “TB is transmitted by inhaling droplets from coughing or sneezing.”
d. “TB is transmitted from one person to another by infected blood.” ANS: C
TB is transmitted by infected humans, cows (bovine), and birds (avian). Droplets ejected during
coughing or sneezing are inhaled by an uninfected host. Once the bacterium is inhaled it rapidly
multiplies in the oxygen-rich lung tissue.
DIF: Cognitive Level: Applying REF: p. 84
2. A patient with a confirmed active tuberculosis (TB) exposure asks how the first-line drugs
such as isoniazid (INH) work to prevent infection. What response demonstrates your
understanding of the action of isoniazid?
a. “INH disrupts blood flow in TB cells depriving them of oxygen.”
b. “INH inhibits enzymes needed for reproduction and growth of TB.”
c. “INH is a bacteriostatic drug that works directly in the lung when inhaled.”
d. “INH works by increasing the elimination of tubercular bacteria through the urine.” ANS: B
Isoniazid (INH) is a bactericidal drug that inhibits the enzymes of the TB organisms needed for
reproduction and growth. INH can inhibit the enzymes of the TB bacteria that are in an
infectious
, as well as a dormant state.
DIF: Cognitive Level: Understanding REF: p. 87
3. Which type of treatment would you expect to be used for a patient with active tuberculosis?
a. Long-term treatment with several antitubercular drugs
b. Prophylactic treatment with isoniazid (INH) only
c. Rifampin for 10 days or until the cough is resolved
d. Ethambutol plus a course of broad-spectrum antibiotics ANS: A
Antitubercular drugs are classified as primary or secondary agents to describe the way they are
used in treating tuberculosis. The combination of drugs helps to slow the development of
bacterial resistance in active TB.
DIF: Cognitive Level: Remembering REF: p. 85
4. You are teaching a patient prescribed rifampin for the treatment of tuberculosis. What
instruction should be included in the treatment plan?
a. “Avoid taking acetaminophen and alcohol while taking this drug.”
b. “Take this drug with milk or an antacid to avoid stomach upset.”
c. “Your stools may be darker than normal when taking this drug.”
d. “Take this drug with food.” ANS: A
Rifampin can cause liver damage that is potentiated by acetaminophen and alcohol. DIF:
Cognitive Level: Applying REF: p. 86
5. A patient receiving antibiotics for the treatment of a bacterial wound infection develops a
secondary fungal infection. The patient asks you to explain why the fungal infection developed.
What is your best response?
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